Chin. J. Org. Chem. ›› 2006, Vol. 26 ›› Issue (10): 1414-1417. Previous Articles     Next Articles




  1. (苏州大学化学化工学院 江苏省有机合成重点实验室 苏州 215123)
  • 收稿日期:2005-11-16 修回日期:2006-02-20 发布日期:2006-09-19
  • 通讯作者: 纪顺俊

Facile Synthesis of Z/E-3-Arylmethylidene-2,3-dihydroindol-2-one under Solvent-Free Conditions

XU Tian-Tu,WANG Shun-Yi,JI Shun-Jun*   

  1. (Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry and Chemical Engineer-ing,
    Suzhou University, Suzhou 215123)
  • Received:2005-11-16 Revised:2006-02-20 Published:2006-09-19
  • Contact: JI Shun-Jun

A series of 3-arylmethylidene-2,3-dihydroindol-2-one derivatives 3 were conveniently synthesized by the condensation of aromatic aldehydes with 2-dihydroindol-2-one under basic and solvent-free conditions by grinding. All the products were determined by 1H NMR, IR, and HRMS spectra, with the configurations of (Z)-3e and (Z)-3j confirmed by X-ray analysis.

Key words: 3-arylmethylidene-2,3-dihydroindol-2-one, 2-oxoindole, knoevenagel condensation, solvent-free