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Chin. J. Org. Chem. ›› 2006, Vol. 26 ›› Issue (11): 1571-1575. Previous Articles     Next Articles

Original Articles

新型含芳氧乙酸酯基三唑酮类化合物的合成及生物活性研究

卢彦昌，刘建兵，梁华，史延年，方建新*   

  1. (南开大学元素有机化学国家重点实验室 元素有机化学研究所 天津 300071)
  • 收稿日期:2005-11-15 修回日期:1900-01-01 发布日期:2006-10-27
  • 通讯作者: 方建新

Synthesis and Biological Activities of 1H-1,2,4-Triazole Derivatives Containing Aryloxyacetate Unit

LU Yan-Chang,LIU Jian-Bing,LIANG Hua,SHI Yan-Nian,FANG Jian-Xin*   

  1. (Institute and State Key Laboratory of Elemento-organic Chemistry, Nankai University, Tianjin 300071)
  • Received:2005-11-15 Revised:1900-01-01 Published:2006-10-27
  • Contact: FANG Jian-Xin

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Fourteen new 1H-1,2,4-triazole derivatives containing aryloxyacetate unit were synthesized by the reaction of 2-bromo-4,4-dimethyl-1-(1H-1,2,4-triazol-1-yl)pentan-3-one with substituted phenoxyacetic acid derivatives, the structures of which have been characterized by 1H NMR and elemental analysis. Bioassay showed that some of them exhibited high biological activities.

Key words: aryloxyacetate, synthesis, biological activity, 1H-1,2,4-triazole