Chin. J. Org. Chem. ›› 2012, Vol. 32 ›› Issue (11): 2177-2180.DOI: 10.6023/cjoc201206010 Previous Articles     Next Articles



邓桂胜a,b, 莫宏华a, 罗景a, 汤力a   

  1. a 湖南师范大学化学化工学院 长沙 410081;
    b 化学生物学及中药分析教育部重点实验室(湖南师范大学) 长沙 410081
  • 收稿日期:2012-06-08 修回日期:2012-06-28 发布日期:2012-07-11
  • 通讯作者: 邓桂胜

Base-Free Method for Preparation of O-Sulfonyl Aldoximes Starting from Aldoximes and Sulfonyl Chlorides

Deng Guishenga,b, Mo Honghuaa, Luo Jinga, Tang Lia   

  1. a College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha 410081;
    b Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research (Hunan Normal University), Ministry of Education, Changsha 410081
  • Received:2012-06-08 Revised:2012-06-28 Published:2012-07-11

A series of O-sulfonyl oxime derivatives have been synthesized by the reaction of oximes with sulfonyl chlorides in the presence of silver oxide and potassium iodide. In the case of aromatic aldoximes and ketoximes, desired products were obtained in 56%~87% yields. But then no desired products were obtained when p-nitrobenzaldoxime, aliphatic aldoximes and α,β-unsaturated aldoximes were employed as substrates in the process.

Key words: O-sulfonyl oximes, synthesis, oximes, sulfonyl chlorides, silver oxide