Chin. J. Org. Chem. ›› 2015, Vol. 35 ›› Issue (1): 232-235.DOI: 10.6023/cjoc201407021 Previous Articles     Next Articles

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3-吗啉基氟化硼络合二吡咯甲川类化合物的合成及反应机理研究

贺琳彦, 胡全子, 席海涛, 孙小强   

  1. 常州大学石油化工学院 常州 213164
  • 收稿日期:2014-07-11 修回日期:2014-09-07 出版日期:2015-01-25 发布日期:2014-09-18
  • 通讯作者: 席海涛 E-mail:xht@cczu.edu.cn
  • 基金资助:

    国家自然科学基金(No. 20872051)资助项目.

Synthesis and Mechanism Study of 3-Morpholin Boron- dipyrrolemethene Derivatives

He Linyan, Hu Quanzi, Xi Haitao, Sun Xiaoqiang   

  1. School of Petrochemical Engineering, Changzhou University, Changzhou 213164
  • Received:2014-07-11 Revised:2014-09-07 Online:2015-01-25 Published:2014-09-18
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No.20872051).

Two new 3-morpholin boron-dipyrrolemethene (BODIPY) derivatives, 4,4-difluoro-8-[4'-(3-morpholinopropoxy)- phenyl]-3-morpholin-4-bora-3a,4a-diaza-s-indacene and 4,4-difluoro-8-(4-methoxyphenyl)-3-morpholin-4-bora-3a,4a-diaza- s-indacene, were designed and synthesized from p-hydroxybenzaldehyde and pyrrole. The key intermediates and the target compounds were characterized by 1H NMR and LC-MS. The mechanism of direct functionalization of BODIPY dyes at the 3-position was investigated with similarity experiments and the crystal structure.

Key words: BODIPY, synthesis, reaction mechanism