关键词: 氧化, 反应动力学, 腺嘌呤核苷, 反应速度常数, 生物分子, 计时电位法, 腺嘌呤, 电化学, 循环伏安法, 单磷酸腺苷

The anodic behavior of 3 biolog. important mols., adenine, adenosine, and 5'-AMP, was comparatively investigated at C paste electrode. The peak potential and peak current for differential pulse voltammetry were studied as a function of pH and concentration The kinetic parameters (bnb) for the rate-detg. step of the oxidation reactions under diffusion-control were measured with linear sweep voltammetry at 10?and pH 3.3, which were 0.77, 0.91, and 0.87, resp. Chronoamperometry was used to determine the diffusion coefficient (D) of these compounds, which were 5.03, 4.21, and 1.59 ?10-6 cm2/s, resp. Using the bnb and D data obtained independently from each other, the heterogeneous rate constants (kb) for the overall anodic processes were calculated and compared.

Key words: OXIDATION, REACTION KINETICS, ADENOSINE, REACTION RATE CONSTANT, BIOMOLECULE, CHRONOPOTONTIOMETRY, ADENINE, ELECTROCHEMISTRY, CYCLOVOLTAMGRAPH, ADENOSINE MONOPHOSPHATE