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封面介绍Glycoproteins play important roles in cellular activities and disease development. In this paper, cleavable bifunctional probes was designed and utilized to enrich cell surface glycoproteins. Due to the mild cleavage condition, the probes would separate labelled glycoproteins from contaminant proteins to exclude the interference of non-glycoproteins which improved the sensitivity and selectivity of the cell surface glycoprotein identification by mass spectrometry (MS). [Tian, Ruijun et al. on page 1673-1680.]
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