Acta Chimica Sinica ›› 2001, Vol. 59 ›› Issue (12): 2181-2185. Previous Articles     Next Articles

Original Articles

多糖与生物探针相互作用机理的研究: 透明质酸与天青A的反应

万晖;欧阳炜;焦庆才;刘茜;周尚根;丁黎华   

  1. 南京大学生命科学学院药物生物技术国家重点实验室
  • 发布日期:2001-12-15

Study on the interaction between polysaccharides and biological probes: Hyaluronic acid and azur A

Wan Hui;Ou Yangwei;Jiao Qingcai;Liu Qian;Zhou Shanggen;Ding Lihua   

  • Published:2001-12-15

The interaction of hyaluronic aicd (HA) and azur A(AA) was studied by absorption spectra. The influence of pH and the molar ratio of AA/HA on the spectra was investigated. The critical molar ratio (1.28×10^3) necessary fro the hypsochromism of the absorption spectra of AA-HA complex and the maximum binding number (3.22×10^3) were obtained by spectrometry. The maximum binding number is consistent with the theoretical value.

Key words: POLYSACCHARIDE, HYALURONIC ACID, INTERACTIONS, REACTION MECHANISM

CLC Number: