Recent Advances in Visible Light Induced Radical 1,2-Functionalization of Alkynes

doi:10.6023/A24030090

Acta Chimica Sinica ›› 2024, Vol. 82 ›› Issue (6): 658-676.DOI: 10.6023/A24030090 Previous Articles Next Articles

Review

可见光介导炔烃的自由基1,2-官能团化反应新进展

李康葵^a, 龙先扬^a, 黄岳^a, 祝诗发^a^,^b^,^*()

a 华南理工大学化学与化工学院广东省功能分子工程重点实验室广州 510640
b 浙江理工大学化学与化工学院杭州 310018

投稿日期:2024-03-18 发布日期:2024-04-28

作者简介:

李康葵, 男, 汉族, 1992年出生于湖南耒阳. 2015年6月本科毕业于怀化学院, 2017年9月考入云南民族大学有机化学专业攻读硕士学位, 导师为樊保敏教授, 于2020年6月毕业并获得理学硕士学位. 同年9月考入华南理工大学攻读博士学位, 在导师祝诗发教授的指导下开展学位论文研究工作, 研究方向为乙炔的高值转化.

龙先扬, 男, 壮族, 2000年出生于广西南宁. 2022年6月本科毕业于广西大学, 同年9月考入华南理工大学, 并加入祝诗发教授课题组攻读硕士学位, 研究方向为乙炔的官能团化反应.

黄岳, 男, 壮族, 2001年出生于广西百色. 2023年6月本科毕业于广西大学, 同年9月考入华南理工大学, 并加入祝诗发教授课题组攻读硕士学位, 研究方向为乙炔的官能团化反应.

祝诗发, 华南理工大学二级教授、博导. 2001年6月本科毕业于湖南大学, 同年考入中科院上海有机所硕博连读, 导师为朱仕正研究员, 2006年6月获中科院上海有机所理学博士学位. 同年9月赴美, 先后在Syracuse University和University of South Florida 从事博士后研究. 2009年5月, 作为“海外优秀引进人才”入职华南理工大学化学与化工学院. 国家自然科学基金-优秀青年基金获得者, 先后入选“教育部新世纪优秀人才支持计划”、“科技部中青年科技创新领军人才和国家“万人计划”科技创新领军人才, 担任Green Synth. Catal.和《有机化学》杂志编委. 研究方向为炔烃的多样性精准转化.

基金资助:
项目受国家自然科学基金(22071062); 项目受国家自然科学基金(22271096); 中央高校基本科研业务费专项资金(2022ZYGXZR107)

Recent Advances in Visible Light Induced Radical 1,2-Functionalization of Alkynes

Kangkui Li^a, Xianyang Long^a, Yue Huang^a, Shifa Zhu^a^,^b,*()

a Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510640
b School of Chemistry and Chemical Engineering, Zhejiang Sci-Tech University, Hangzhou 310018

Received:2024-03-18 Published:2024-04-28
Contact: * E-mail: zhusf@scut.edu.cn
Supported by:
National Natural Science Foundation of China(22071062); National Natural Science Foundation of China(22271096); Fundamental Research Funds for the Central Universities, SCUT(2022ZYGXZR107)

As one of the most basic functional groups in organic molecules, the carbon-carbon triple bond containing two π-bonds harbor great potential for diverse organic transformations. Among them, the functionalization reaction based on the addition of free radicals to alkynes is an effective way to synthesize diverse functionalized olefins, ketones, and even alkane molecules, as well as an important tool for constructing multiple chemical bonds simultaneously. In the last decade, the application of visible light-induced radical reaction strategy for alkyne functionalization has received widespread attention due to it align with the concepts of green chemistry and sustainable development. Nowadays, photoinduced radical functionalization of alkynes has been developed unprecedentically, and many new methods have emerged. Indeed, light-induced radical functionalization reactions of alkynes provide a relatively green approach to the diverse transformations of alkynes. These conversions include hydrofunctionalization, oxidative functionalization, difunctionalization, and so on. These reactions feature mild conditions and easy operation, and do not even require the addition of metals and photosensitizers. Importantly, they provide an efficient way for the construction of valuable skeletons. In particular, the difunctionalization reaction enables the synthesis of high-added-value challenging molecules from simple feedstocks. In these reactions, the alkenyl radicals formed by radical addition to alkynes are the key intermediates. Thus, the type of radical precursor and the further transformation of the alkenyl radical determine the type of chemical bond constructed and the structure of the final product. This paper mainly reviews the new advances in photoinduced radical 1,2-functionalization reactions of alkynes in the past five years, classifying them in terms of the types of chemical bonds constructed, and providing a systematic summary of the types of radicals and reactions. The mechanism and universality of the reactions, as well as its advantages and disadvantages were discussed, and the challenges and opportunities facing the field were outlooked as well.

Key words: visible light, alkynes, radical reaction, functionalization, photocatalysis

Cite this article

Kangkui Li, Xianyang Long, Yue Huang, Shifa Zhu. Recent Advances in Visible Light Induced Radical 1,2-Functionalization of Alkynes[J]. Acta Chimica Sinica, 2024, 82(6): 658-676.

Export EndNote|Reference Manager|ProCite|BibTeX|RefWorks

share this article

Fig. & Tab. 55

Figure 1. Photoinduced radical functionalization of alkynes

Figure 2. General process of radical hydrofunctionalization of alkynes

Figure 3. Photocatalyzed hydrotrifluoromethylation of alkynes

Figure 4. Light/high-valent iodine-induced hydrodifluoromethylation of alkynes

Figure 5. Photoinduced difluoroalkylation of alkynes

Figure 6. Photoredox/nickel dual catalyzed hydroalkylation of alkynes

Figure 7. Photoinduced/copper-catalyzed hydroalkylation of terminal alkynes

Figure 8. Photocatalyzed hydroalkylation of terminal alkynes

Figure 9. Photoredox/nickel dual catalyzed hydroalkylation of alkynes

Figure 10. Photocatalyzed hydroarylation of terminal alkynes

Figure 11. Photocatalyzed cis-hydrophosphination of alkynes

Figure 12. Photoinduced hydrophosphylation of alkynes

Figure 13. Photocatalyzed hydrophosphination reaction of alkynes

Figure 14. Photocatalytic reaction of alkynes with thiophenols or mercaptans

Figure 15. Diverse thioetherification reactions of alkynes

Figure 16. Photocatalyzed hydrogen-sulfonylation of alkynes

Figure 17. Photoredox/copper dual catalyzed alkyne hydroboronation reaction

Figure 18. Photocatalyzed three-component hydrosulfurization of alkynes

Figure 19. Photoredox/nickel dual catalyzed functionalization of alkyne

Figure 20. General pathway of radical oxidation-functionalization of alkynes

Figure 21. Photocatalyzed multicomponent oxidative trifluoromethylation of alkynes

Figure 22. Visible-light-induced reaction of alkyne and arylazo sulfone

Figure 23. Oxidation-thiocyanation reaction of alkynes

Figure 24. Oxidation-sulfonylation of alkynes

Figure 25. Photoinduced phosphonylation-oxidation of alkynes

Figure 26. General process of radical bifunctional process of alkynes

Figure 27. General pathway of photoredox/nickel dual catalyzed three-component cross-coupling reaction of alkyne

Figure 28. Photoredox/nickel dual catalyzed Z-aryl-alkylation of alkynes

Figure 29. Photoredox/nickel dual catalyzed alkyl-arylation of alkynes

Figure 30. Photoredox/nickel dual catalyzed allyl-alkylation of terminal alkynes

Figure 31. Photocatalyzed reaction of keto acids and alkynes

Figure 32. Photocatalyzed double-carbon functionalization of acetylene

Figure 33. Photocatalyzed bis-cyanation of alkynes

Figure 34. Photocatalyzed two-carbon functionalization of alkynes

Figure 35. Photocatalyzed trifluoromethyl-halogenation of alkynes

Figure 36. Photoinduced sulfonylation-trifluoromethylation of alkynes

Figure 37. Photoinduced cyanomethyl-iodination of alkynes

Figure 38. Photoinduced perfluoroalkyl-iodination of alkynes

Figure 39. Photoinduced CO2-involved difunctionalization of alkynes

Figure 40. Radical cycloaddition of quaternary phosphines with alkynes

Figure 41. Photoredox/nickel dual catalyzed aryl-sulfonylation of alkynes

Figure 42. Photoredox/Ni dual catalyzed alkenyl-sulfonylation of alkynes

Figure 43. Photoredox/nickel dual catalyzed aryl-bromination of alkynes

Figure 44. Photocatalyzed bisphosphonylation and phosphonylation-alkylation of acetylene

Figure 45. Photocatalyzed dihydrosulfurization of acetylene

Figure 46. Sulfonyl-thioetherylation of acetylene

Figure 47. Photocatalyzed sulfonylation-bromination of acetylene

Figure 48. Photocatalyzed alkyne sulfonyl-chlorination reaction

Figure 49. Light/gold dual catalyzed sulfonation of alkynes

Figure 50. Photocatalyzed radical cascade difunctionalization of alkynes

Figure 51. Photocatalyzed alkyne fluorosulfonyl-chlorination

Figure 52. Photocatalyzed sulfonylation-iodination of alkynes

Figure 53. Light-promoted sulfonylation-iodination of alkynes

Figure 54. Photocatalyzed sulfonyl-disulfide etheration of alkynes

Figure 55. Photocatalyzed sulfonyl-thioetherification of alkynes

References 56

[1]	(a) Gleiter, R.; Werz, D. B. Chem. Rev. 2010, 110, 4447. doi: 10.1021/cr9003727 pmid: 31975673
	(b) Brand, J. P.; Waser, J. Chem. Soc. Rev. 2012, 41, 4165. pmid: 31975673
	(c) Bhunia, S.; Ghosh, P.; Patra, S. R. Adv. Synth. Catal. 2020, 362, 3664. pmid: 31975673
	(d) Heravi, M. M.; Dehghani, M.; Zadsirjan, V.; Ghanbarian, M. Curr. Org. Synth. 2019, 16, 205. doi: 10.2174/1570179416666190126100744 pmid: 31975673
	(e) Chen, L.; Chen, K.; Zhu, S. Chem 2018, 4, 1208. pmid: 31975673
	(f) Patel, M.; Saunthwal, R. K.; Verma, A. K. Acc. Chem. Res. 2017, 50, 240. pmid: 31975673
	(g) Alabugin, I. V.; Gonzalez-Rodriguez, E. Acc. Chem. Res. 2018, 51, 1206. pmid: 31975673
	(h) Fang, G.; Bi, X. Chem. Soc. Rev. 2015, 44, 8124. pmid: 31975673
	(i) Khan, R.; Chen, J.; Fan, B. Adv. Synth. Catal. 2020, 362, 1564. pmid: 31975673
[2]	(a) Wille, U. Chem. Rev. 2013, 113, 813. doi: 10.1021/cr100359d pmid: 23121090
	(b) Hu, C.; Mena, J.; Alabugin, I. V. Nat. Rev. Chem. 2023, 7, 405. pmid: 23121090
	(c) Ren, X.; Lu, Z. Chin. J. Catal. 2019, 40, 1003. pmid: 23121090
	(d) Chalotra, N.; Kumar, J.; Naqvi, T.; Shah, B. A. Chem. Commun. 2021, 57, 11285. pmid: 23121090
	(e) Bag, D.; Kour, H.; Sawant, S. D. Org. Biomol. Chem. 2020, 18, 8278. pmid: 23121090
[3]	(a) Zhang, Y.; Cai, Z.; Warratz, S.; Ma, C.; Ackermann, L. Sci. China Chem. 2023, 66, 703.
	(b) Deng, W.; Li, Y.; Li, Y.-G.; Bao, H. Synthesis 2018, 50, 2974.
	(c) Ma, J.; Li, J.; Meng, Q.; Zeng, X. Chin. J. Org. Chem. 2023, 43, 2040. (in Chinese)
	(马佳敏, 李姣兄, 孟千森, 曾祥华, 有机化学, 2023, 43, 2040.) doi: 10.6023/cjoc202210015
[4]	(a) Romero, N. A.; Nicewicz, D. A. Chem. Rev. 2016, 116, 10075. pmid: 30291664
	(b) Prier, C. K.; Rankic, D. A.; MacMillan, D. W. C. Chem. Rev. 2013, 113, 5322. pmid: 30291664
	(c) Milligan, J. A.; Phelan, J. P.; Badir, S. O.; Molander, G. A. Angew. Chem. Int. Ed. 2019, 58, 6152. doi: 10.1002/anie.201809431 pmid: 30291664
	(d) Gao, P.-P.; Xiao, W.-J.; Chen, J.-R. Chin. J. Org. Chem. 2022, 42, 3923. (in Chinese) pmid: 30291664
	(高盼盼, 肖文精, 陈加荣, 有机化学, 2022, 42, 3923.) doi: 10.6023/cjoc202208044 pmid: 30291664
	(e) Wang, H.; Wu, P.; Zhao, X.; Zeng, J.; Wan, Q. Acta Chim. Sinica 2019, 77, 231. (in Chinese) doi: 10.6023/A18100429 pmid: 30291664
	(王浩, 吴品儒, 赵祥, 曾静, 万谦, 化学学报, 2019, 77, 231.) doi: 10.6023/A18100429 pmid: 30291664
	(f) Laishram, R. D.; Chen, J.; Fan, B. Chem. Rec. 2021, 21, 69. pmid: 30291664
	(g) Zhang, J.; Chen, Y. Acta Chim. Sinica 2017, 75, 41. (in Chinese) doi: 10.6023/A16080416 pmid: 30291664
	(张晶, 陈以昀, 化学学报, 2017, 75, 41.) doi: 10.6023/A16080416 pmid: 30291664
	(h) Wang, D.; Zhang, L.; Luo, S. Acta Chim. Sinica 2017, 75, 22. (in Chinese) pmid: 30291664
	(王德红, 张龙, 罗三中, 化学学报, 2017, 75, 22.) doi: 10.6023/A16080418 pmid: 30291664
[5]	Giese, B.; Lachhein, S. Angew. Chem., Int. Ed. Engl. 1982, 21, 768.
[6]	(a) Zheng, H.; Su, J.; Zhou, Y.; Zhu, G. Chin. J. Org. Chem. 2022, 42, 4060. (in Chinese)
	(郑汉良, 苏静雯, 周雨露, 朱钢国, 有机化学, 2022, 42, 4060.) doi: 10.6023/cjoc202209029
	(b) Liao, J.; Yang, X.; Ouyang, L.; Lai, Y.; Huang, J.; Luo, R. Org. Chem. Front. 2021, 8, 1345.
	(c) Zhou, Y.; Gu, Z.; Hong, Y.; Chen, H.; Luo, J.; Zheng, H.; Zhu, G. Org. Chem. Front. 2024, 11, 1232.
[7]	Ren, Y.-Y.; Zheng, X.; Zhang, X. Synlett 2018, 29, 1028.
[8]	Meyer, C. F.; Hell, S. M.; Misale, A.; Trabanco, A. A.; Gouverneur, V. Angew. Chem. Int. Ed. 2019, 58, 8829.
[9]	Li, K.; Zhang, X.; Chen, J.; Gao, Y.; Yang, C.; Zhang, K.; Zhou, Y.; Fan, B. Org. Lett. 2019, 21, 9914.
[10]	Deng, H.-P.; Fan, X.-Z.; Chen, Z.-H.; Xu, Q.-H.; Wu, J. J. Am. Chem. Soc. 2017, 139, 13579.
[11]	Song, Z.-Q.; Liu, Z.; Gan, Q.-C.; Lei, T.; Tung, C.-H.; Wu, L.-Z. Org. Lett. 2020, 22, 832.
[12]	Liu, F.; Zhang, K.; Zhao, X.-F.; Meng, Q.-X.; Zhao, T.-S.; Tian, W.-F.; He, Y.-Q. Tetrahedron Lett. 2023, 115, 154321.
[13]	Yue, H.; Zhu, C.; Kancherla, R.; Liu, F.; Rueping, M. Angew. Chem. Int. Ed. 2020, 59, 5738.
[14]	Lai, S.-Z.; Yang, Y.-M.; Xu, H.; Tang, Z.-Y.; Luo, Z. J. Org. Chem. 2020, 85, 15638.
[15]	Wang, H.; Li, Y.; Tang, Z.; Wang, S.; Zhang, H.; Cong, H.; Lei, A. ACS Catal. 2018, 8, 10599.
[16]	Huang, T.; Saga, Y.; Guo, H.; Yoshimura, A.; Ogawa, A.; Han, L.-B. J. Org. Chem. 2018, 83, 8743.
[17]	Ikeshita, D.; Masuda, Y.; Ishida, N.; Murakami, M. Org. Lett. 2022, 24, 2504.
[18]	Kaur, S.; Zhao, G.; Busch, E.; Wang, T. Org. Biomol. Chem. 2019, 17, 1955.
[19]	Burykina, J. V.; Shlapakov, N. S.; Gordeev, E. G.; König, B.; Ananikov, V. P. Chem. Sci. 2020, 11, 10061. doi: 10.1039/d0sc01939a pmid: 34094267
[20]	Wu, X.; Gao, B. Org. Lett. 2023, 25, 8722.
[21]	Zhong, M.; Gagné, Y.; Hope, T. O.; Pannecoucke, X.; Frenette, M.; Jubault, P.; Poisson, T. Angew. Chem. Int. Ed. 2021, 60, 14498.
[22]	Tang, H.; Zhang, M.; Zhang, Y.; Luo, P.; Ravelli, D.; Wu, J. J. Am. Chem. Soc. 2023, 145, 5846.
[23]	Huo, L.; Li, X.; Zhao, Y.; Li, L.; Chu, L. J. Am. Chem. Soc. 2023, 145, 9876.
[24]	Malpani, Y. R.; Biswas, B. K.; Han, H. S.; Jung, Y.-S.; Han, S. B. Org. Lett. 2018, 20, 1693.
[25]	Lv, Y.; Liu, Q.; Liu, F.; Yue, H.; Li, J.-S.; Wei, W. Tetrahedron Lett. 2020, 61, 151335.
[26]	Hosseini-Sarvari, M.; Valikhani, A. New J. Chem. 2021, 45, 12464.
[27]	Song, T.; Zhang, Y.; Wang, C.; Li, Y.; Yang, Y. Chin. J. Chem. 2022, 40, 2618.
[28]	Liu, L.; Liu, M.; Liu, B.; Wang, Q.; Li, Y.; Feng, K.; Qiu, R.; Zhou, Y. Tetrahedron Lett. 2023, 133, 154823.
[29]	(a) Badir, S. O.; Molander, G. A. Chem 2020, 6, 1327.
	(b) Zhu, C.; Yue, H.; Chu, L.; Rueping, M. Chem. Sci. 2020, 11, 4051.
	(c) Zhu, S.; Zhao, X.; Li, H.; Chu, L. Chem. Soc. Rev. 2021, 50, 10836.
	(d) Dong, Y.-J.; Zhu, B.; Geng, Y.; Zhao, Z.-W.; Su, Z.-M.; Guan, W. CCS Chem. 2021, 4, 1429.
	(e) Xu, L.; Wang, F.; Chen, F.; Zhu, S.; Chu, L. Chin. J. Org. Chem. 2022, 42, 1. (in Chinese)
	(徐磊, 王方, 陈凡, 朱圣卿, 储玲玲, 有机化学, 2022, 42, 1.) doi: 10.6023/cjoc202109002
[30]	Guo, L.; Song, F.; Zhu, S.; Li, H.; Chu, L. Nat. Commun. 2018, 9, 4543.
[31]	Qin, J.; Zhang, Z.; Lu, Y.; Zhu, S.; Chu, L. Chem. Sci. 2023, 14, 12143.
[32]	Yang, B.; Li, S.-J.; Wang, Y.; Lan, Y.; Zhu, S. Nat. Commun. 2021, 12, 5257. doi: 10.1038/s41467-021-25594-4 pmid: 34489468
[33]	Yang, B.; Lu, S.; Wang, Y.; Zhu, S. Nat. Commun. 2022, 13, 1858. doi: 10.1038/s41467-022-29556-2 pmid: 35388000
[34]	Zhang, Y.; Han, Y.; Zhu, S.; Qing, F.-L.; Xue, X.-S.; Chu, L. Angew. Chem. Int. Ed. 2022, 61, e202210838.
[35]	Wang, J.; Wu, X.; Cao, Z.; Zhang, X.; Wang, X.; Li, J.; Zhu, C. Adv. Sci. 2024, 2309022.
[36]	Lee, W.; Lee, Y.; Yoo, M.; Han, S. B.; Kim, H. J. Org. Chem. Front. 2020, 7, 3209.
[37]	Dong, X.; Jiang, W.; Hua, D.; Wang, X.; Xu, L.; Wu, X. Chem. Sci. 2021, 12, 11762.
[38]	Pan, C.; Meng, Y.; Deng, Y.; Zhou, B.; Chen, J.; He, Z.; Sun, W.; Khan, R.; Fan, B. Chin. J. Chem. 2022, 40, 2040.
[39]	Wang, Y.; Cao, Z.; He, Q.; Huang, X.; Liu, J.; Neumann, H.; Chen, G.; Beller, M. Chem. Sci. 2023, 14, 1732.
[40]	Miao, M.; Zhu, L.; Zhao, H.; Song, L.; Yan, S.-S.; Liao, L.-L.; Ye, J.-H.; Lan, Y.; Yu, D.-G. Sci. China Chem. 2023, 66, 1457.
[41]	Masuda, Y.; Ikeshita, D.; Higashida, K.; Yoshida, M.; Ishida, N.; Murakami, M.; Sawamura, M. J. Am. Chem. Soc. 2023, 145, 19060.
[42]	Zhu, C.; Yue, H.; Maity, B.; Atodiresei, I.; Cavallo, L.; Rueping, M. Nat. Catal. 2019, 2, 678.
[43]	Long, T.; Zhu, C.; Li, L.; Shao, L.; Zhu, S.; Rueping, M.; Chu, L. Nat. Commun. 2023, 14, 55.
[44]	Xu, L.; Zhu, S.; Huo, L.; Chen, F.; Yu, W.; Chu, L. Org. Chem. Front. 2021, 8, 2924.
[45]	Li, K.; Deng, J.; Long, X.; Zhu, S. Green Chem. 2023, 25, 7253.
[46]	Lü, S.; Wang, Z.; Zhu, S. Nat. Commun. 2022, 13, 5001.
[47]	Lü, S.; Wang, Z.; Gao, X.; Chen, K.; Zhu, S. Angew. Chem. Int. Ed. 2023, 62, e202300268.
[48]	Yang, B.; Li, K.; Wang, Y.; Zhu, S. Sci. China Chem. 2024, 67, 936.
[49]	Chakrasali, P.; Kim, K.; Jung, Y.-S.; Kim, H.; Han, S. B. Org. Lett. 2018, 20, 7509. doi: 10.1021/acs.orglett.8b03273 pmid: 30489090
[50]	Li, H.; Cheng, Z.; Tung, C.-H.; Xu, Z. ACS Catal. 2018, 8, 8237.
[51]	Sahoo, A. K.; Dahiya, A.; Das, B.; Behera, A.; Patel, B. K. J. Org. Chem. 2021, 86, 11968.
[52]	Nie, X.; Xu, T.; Hong, Y.; Zhang, H.; Mao, C.; Liao, S. Angew. Chem. Int. Ed. 2021, 60, 22035.
[53]	Kumar, S.; Kumar, J.; Naqvi, T.; Raheem, S.; Rizvi, M. A.; Shah, B. A. ChemPhotoChem 2022, 6, e202200110.
[54]	Abramov, V. A.; Topchiy, M. A.; Rasskazova, M. A.; Drokin, E. A.; Sterligov, G. K.; Shurupova, O. V.; Malysheva, A. S.; Rzhevskiy, S. A.; Beletskaya, I. P.; Asachenko, A. F. Org. Biomol. Chem. 2023, 21, 3844.
[55]	Ren, X.; Ke, Q.; Zhou, Y.; Jiao, J.; Li, G.; Cao, S.; Wang, X.; Gao, Q.; Wang, X. Angew. Chem. Int. Ed. 2023, 62, e202302199.
[56]	Xie, S.-L.; Yan, J.-Z.; Xie, M.-J.; Li, X.; Zhou, F.; Zheng, M.-Q.; Wang, X.-L.; Feng, J.; Zhang, Y.; Duan, Y.-N.; Niu, Y.-D.; Li, D.; Xia, H.-D. Green Chem. 2024, 26, 323.

可见光介导炔烃的自由基1,2-官能团化反应新进展

Recent Advances in Visible Light Induced Radical 1,2-Functionalization of Alkynes

RichHTML

PDF

Knowledge

Abstract

Cite this article

share this article

Fig. & Tab. 55

References 56

Related Articles 15

Recommended Articles

Metrics

Comments

[1]	Haoning Zheng, Jinyu Liu. Research Progress on Organocatalytic Functionalization of Indole in the Carbocyclic Ring [J]. Acta Chimica Sinica, 2024, 82(6): 641-657.
[2]	Hao Liu, Xuli Xu, Yong Guo, Xiaohui Liu, Yanqin Wang. Efficient Electro-catalytic Reductive Amination of Aldehyde over Ru Deposited on Nickel Phosphate [J]. Acta Chimica Sinica, 2024, 82(5): 477-485.
[3]	Guangzheng Huang, Kunwei Li, Yannan Luo, Qiang Zhang, Yuanlong Pan, Honglin Gao. Hydrothermal Treatment for Constructing K Doping and Surface Defects in g-C₃N₄ Nanosheets Promote Photocatalytic Hydrogen Production [J]. Acta Chimica Sinica, 2024, 82(3): 314-322.
[4]	Cheng-Qiang Wang, Chao Feng. Applications of Nucleophilic Fluorine Sources in the Selective Fluorofunctionalization of Unsaturated Carbon-Carbon Bonds [J]. Acta Chimica Sinica, 2024, 82(2): 160-170.
[5]	Shenna Deng, Changchun Peng, Yunhong Niu, Yun Xu, Yunxiao Zhang, Xiang Chen, Hongmin Wang, Shanshan Liu, Xiao Shen. Radical Brook Rearrangement Mediated Olefin Difunctionalization Involving α-Fluoroalkyl-α-silyl Methanols [J]. Acta Chimica Sinica, 2024, 82(2): 119-125.
[6]	Jianqiang Chen, Gangguo Zhu, Jie Wu. Recent Advances in Nickel-Catalyzed Ring Opening Cross-Coupling of Aziridines [J]. Acta Chimica Sinica, 2024, 82(2): 190-212.
[7]	Xianting Huang, Hongliang Han, Jing Xiao, Fan Wang, Zhong-Quan Liu. An I₂O₅/KSCN-Mediated Iodothiocyanation of Alkynes [J]. Acta Chimica Sinica, 2024, 82(1): 5-8.
[8]	Yuhan Wu, Dongdong Zhang, Hongyu Yin, Zhengnan Chen, Wen Zhao, Yuhua Chi. Density Functional Theory Study of Janus In₂S₂X Photocatalytic Reduction of CO₂ under “Double Carbon” Target [J]. Acta Chimica Sinica, 2023, 81(9): 1148-1156.
[9]	Lefei Yu, Xing-Qi Yao, Jianbo Wang. Recent Advance of Diazo Compounds in Polymer Synthesis^★ [J]. Acta Chimica Sinica, 2023, 81(8): 1015-1029.
[10]	Minghui He, Ziqiu Ye, Guiqing Lin, Sheng Yin, Xinyi Huang, Xu Zhou, Ying Yin, Bo Gui, Cheng Wang. Research Progress of Porphyrin-Based Covalent Organic Frameworks in Photocatalysis^★ [J]. Acta Chimica Sinica, 2023, 81(7): 784-792.
[11]	Sinan Du, Liman Zhao, Zexin Zhang, Guosong Chen. Preparation and Preliminary Study on Immune Function of Mannose-modified Micromotor^★ [J]. Acta Chimica Sinica, 2023, 81(7): 741-748.
[12]	Jiawen Liu, Weihuang Lin, Weijia Wang, Xueyi Guo, Ying Yang. Synthesis and Photocatalytic Degradation of Cu_1.94S-SnS Nano-heterojunction [J]. Acta Chimica Sinica, 2023, 81(7): 725-734.
[13]	Li Liu, Gang Zheng, Guoqiang Fan, Hongguang Du, Jiajing Tan. Research Progress in Organic Reactions Involving 4-Acyl/Carbamoyl/Alkoxycarbonyl Substituted Hantzsch Esters [J]. Acta Chimica Sinica, 2023, 81(6): 657-668.
[14]	Fei Li, Huili Ding, Chaozhong Li. Hydrotrifluoromethylation of Alkenes with a Fluoroform-Derived Trifluoromethylboron Complex [J]. Acta Chimica Sinica, 2023, 81(6): 577-581.
[15]	Qi Xueping, Wang Fei, Zhang Jian. A Post-Synthetic Method for the Construction of Titanium-Based Metal Organic Frameworks and Their Applications [J]. Acta Chimica Sinica, 2023, 81(5): 548-558.