有机化学 ›› 2012, Vol. 32 ›› Issue (05): 966-972.DOI: 10.6023/cjoc1109041 上一篇    下一篇

学术动态

天然番荔枝内酯类化合物构效关系研究进展

陈勇, 李祥, 陈建伟   

  1. 南京中医药大学药学院 南京 210046
  • 收稿日期:2011-09-04 修回日期:2011-11-17 发布日期:2012-01-07
  • 通讯作者: 李祥 E-mail:lixiang_8182@163.com
  • 基金资助:

    江苏省高校优势学科建设工程(No. ysxk-2010)、国家教育部博士点专项基金(No. 20113237110009)、江苏省中药药效与安全性评价重点实验室(No.P09018)开放研究课题和2011 江苏省普通高校研究生科研创新计划(No. 790)资助项目.

Progress in Structure Activity Relationship of Natural Annonaceous Acetogenins

Chen Yong, Li Xiang, Chen Jianwei   

  1. College of Pharmaceutical Science, Nanjing University of Chinese Medicine, Nanjing 210046
  • Received:2011-09-04 Revised:2011-11-17 Published:2012-01-07
  • Supported by:

    Project supported by the Priority Academic Program Development of Jiangsu Higher Education Institutions (No. ysxk-2010), the Doctoral Fund of Ministry of Education of China (No. 20113237110009), the Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica (No. P09018) and the 2011 Program Sponsored for Scientific Innovation Research of College Graduate in Jiangsu Province (No. 790).

番荔枝内酯类化合物化学结构及抗肿瘤作用机制独特. 综述了这类天然化合物的构效关系研究进展.

关键词: 番荔枝内酯, 构效关系, 进展

Annonaceous acetogenins are characterized by special chemical structures and antitumor mechanism. In this paper, the advance in structure activity relationship of natural annonaceous acetogenins is reviewed.

Key words: annonaceous acetogenin, structure activity relationship, progress