有机化学 ›› 2017, Vol. 37 ›› Issue (4): 1040-1045.DOI: 10.6023/cjoc201611025 上一篇    下一篇

研究简报

铜试剂介导下烯胺酮的氧化环化/迁移合成取代的2H-氮杂丙烯啶的方法

杨坤, 段希焱, 李军波, 刘普, 郭旭明, 李军, 周惠云, 刘宁, 刘建伟, 王双双, 李绘闲, 杜亚珍, 马军营   

  1. 河南科技大学化工与制药学院 洛阳 471023
  • 收稿日期:2016-11-22 修回日期:2016-12-08 发布日期:2016-12-29
  • 通讯作者: 段希焱, 马军营 E-mail:duanxiyan@tju.edu.cn;majy379@haust.edu.cn
  • 基金资助:

    河南科技大学博士科研启动(No.4008-13480042)资助项目.

Copper-Promoted Oxidative Cyclization/Migration of Enaminone for Synthesis of Functionalized 2H-Azirines

Yang Kun, Duan Xiyan, Li Junbo, Liu Pu, Guo Xuming, Li Jun, Zhou Huiyun, Liu Ning, Liu Jianwei, Wang Shuangshuang, Li Huixian, Du Yazhen, Ma Junying   

  1. School of Chemical Engineering & Pharmaceutics, Henan University of Science and Technology, Luoyang 471023
  • Received:2016-11-22 Revised:2016-12-08 Published:2016-12-29
  • Contact: 10.6023/cjoc201611025 E-mail:duanxiyan@tju.edu.cn;majy379@haust.edu.cn
  • Supported by:

    Project supported by the Students Research Training Program of Henan University of Science and Technology (No. 4008-13480042).

报道了铜试剂介导下烯胺酮化合物通过氧化环化/迁移反应合成2-苯酰氧基-2H-氮杂丙烯啶的新方法. 该方法具有反应条件温和、反应时间短和操作简单等优点.

关键词: 铜介导, 氮杂丙烯啶, 烯胺酮, 氧化环化/迁移

A new method for the synthesis of 2-benzoylated 2H-azirine via Cu-promoted oxidative cyclization/migration of enaminone was reported. The advantage of our approach is mild reaction condition, short reaction time and easy operation.

Key words: copper-promoted, 2H-azirines, enaminone, oxidative cyclization/migration