有机化学 ›› 2017, Vol. 37 ›› Issue (11): 3024-3030.DOI: 10.6023/cjoc201702024 上一篇    下一篇

研究简报

通过不同荧光现象识别Cu2+和Zn2+的双吡唑啉荧光探针

杨云裳, 曹碧霞, 张应鹏, 董玉莹   

  1. 兰州理工大学石油化工学院 兰州 730050
  • 收稿日期:2017-02-19 修回日期:2017-06-30 发布日期:2017-08-09
  • 通讯作者: 杨云裳, 张应鹏 E-mail:yangyunshang@tom.com;yingpengzhang@126.com
  • 基金资助:

    甘肃省自然科学基金(No.2014GS03265)资助项目.

Bispyrazoline Fluorescent Probe for the Recognition of Cu2+ and Zn2+ with Different Fluorescence

Yang Yunshang, Cao Bixia, Zhang Yingpeng, Dong Yuying   

  1. School of Petrochemical Engineering, Lanzhou University of Technology, Lanzhou 730050
  • Received:2017-02-19 Revised:2017-06-30 Published:2017-08-09
  • Contact: 10.6023/cjoc201702024 E-mail:yangyunshang@tom.com;yingpengzhang@126.com
  • Supported by:

    Project supported by the Natural Science Foundation of Gansu Province (No. 2014GS03265).

设计合成了一个基于双吡唑啉结构的双功能荧光探针1,1'-(5,5'-(6,6'-二羟基-5,5'-二甲氧基联苯-3,3'-二基)双(3-(2-羟基苯基)-1H-吡唑-5,1-(4H,5H)-二基))二乙酮(C1).利用核磁共振氢谱、碳谱、质谱及元素分析对其结构进行了表征,并通过紫外吸收光谱和荧光光谱研究了探针C1及其对金属离子在4-羟乙基哌嗪乙磺酸(HEPES)缓冲溶液[V(MeOH):V(H2O)=1:1,20 mol·L-1,pH=7.4]中的选择性识别作用.结果表明,探针C1对Cu2+和Zn2+有着较高的选择性和灵敏度,并能通过不同的荧光现象对目标离子的识别加以区分.

关键词: 双吡唑啉, 双功能, 荧光探针, 铜离子, 锌离子

A bifunctional fluorescent probe 1,1'-(5,5'-(6,6'-dihydroxy-5,5'-dimethoxybiphenyl-3,3'-diyl)bis(3-(2-hydroxy-phenyl)-1H-pyrazole-5,1(4H,5H)-diyl))diethanone (C1) based on bispyrazoline was designed and synthesized. The structure of C1 was confirmed by 1H NMR, 13C NMR, MS and elemental analysis. The spectroscopic behavior toward metal ions has been investigated by the absorption and fluorescence methods. It exhibited high sensitivity and selectivity for detecting Cu2+ and Zn2+ over other commonly coexistent metal ions in 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid (HEPES) buffer solution[V(MeOH):V(H2O)=1:1, 20 mol·L-1, pH=7.4] and it has the capability to differentiate target ions with different flu-orescence.

Key words: bispyrazoline, bifunctional, fluorescent probe, copper ion, zinc ion