有机化学 ›› 2021, Vol. 41 ›› Issue (3): 1117-1123.DOI: 10.6023/cjoc202009001 上一篇    下一篇

研究论文

一氟甲基二硫化物的高效合成

胡晓光a, 庞仁艺a, 郑天骄a, 姚瑞超a, 陈文博a,b,*()   

  1. a 上海电力大学环境与化学工程学院 上海市电力材料防护与新材料重点实验室 上海 200090
    b 中国科学院上海有机化学研究所 中科院能量调控材料重点实验室 上海 200032
  • 收稿日期:2020-09-01 修回日期:2020-11-02 发布日期:2020-12-01
  • 通讯作者: 陈文博
  • 基金资助:
    上海市自然科学基金(20ZR1471600); 上海市科学技术委员会(19DZ2271100); 中国科学院能量调控材料重点实验室开放基金(ORFP2020-06)

High Efficient Synthesis of Monofluoromethyldisulfides

Xiaoguang Hua, Renyi Panga, Tianjiao Zhenga, Ruichao Yaoa, Wenbo Chena,b,*()   

  1. a Shanghai Key Laboratory of Materials Protection and Advanced Materials in Electric Power, College of Environmental and Chemical Engineering, Shanghai University of Electric Power, Shanghai 200090
    b CAS Key Laboratory of Energy Regulation Materials, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032
  • Received:2020-09-01 Revised:2020-11-02 Published:2020-12-01
  • Contact: Wenbo Chen
  • About author:
    * Corresponding author. E-mail:
  • Supported by:
    Natural Science Foundation of Shanghai(20ZR1471600); Science and Technology Commission of Shanghai Municipality(19DZ2271100); Open Research Fund Program of CAS Key Laboratory Of Energy Regulation Materials(ORFP2020-06)

以PhSO2SCH2F为一氟甲硫基化试剂, 室温下实现了硫酚/硫醇的一氟甲硫基化反应, 高收率地合成了一系列一氟甲基二硫化物. 该方法具有反应时间短、条件温和、操作简单以及无需外加添加剂等特点, 为高效制备一氟甲基二硫化物提供了一条简便的途径.

关键词: 一氟甲硫基, 二硫化物, PhSO2SCH2F, 硫酚

The monofluoromethylthiolation reaction of thiophenols/mercaptans was developed at room temperature using PhSO2SCH2F as monofluoromethylthiolation reagent, and a series of monofluoromethyl disulfides were synthesized in good yields. This method features short reaction time, mild conditions, simple operation and no additives. It provides a simple and convenient way for the efficient preparation of monofluoromethyl disulfides.

Key words: monofluoromethylthio, disulfide, PhSO2SCH2F, thiophenol