有机化学 ›› 2013, Vol. 33 ›› Issue (02): 343-347.DOI: 10.6023/cjoc201209008 上一篇    下一篇

研究论文

无碱参与的铜催化芳基硼酸和硫酚的偶联反应研究

杨明华, 裴吉, 严国兵, 翁秋月   

  1. 丽水学院理学院 丽水 323000
  • 收稿日期:2012-09-06 修回日期:2012-10-17 发布日期:2012-10-25
  • 通讯作者: 杨明华 E-mail:mhyang@lsu.edu.cn
  • 基金资助:

    浙江省自然科学基金(No. Y407081)资助项目.

Base-Free Cu(II)-Catalyzed Coupling Reaction of Arylboronic Acids and Thiols

Yang Minghua, Pei Ji, Yan Guobing, Weng Qiuyue   

  1. Colllege of Science, Lishui Universtiy, Lishui 323000
  • Received:2012-09-06 Revised:2012-10-17 Published:2012-10-25
  • Supported by:

    Project supported by the Natural Science Foundation of Zhejiang Province (No. Y407081).

无碱参与的条件下, 研究了Cu盐催化芳基硼酸与硫酚的偶联反应. 通过反应溶剂、温度、铜盐、配体等条件的优化, 结果表明在空气中, 以1,10-菲啰啉-醋酸铜为催化剂, DMSO/H2O (V: V=1:1)作为溶剂, 反应温度为60℃, 以较高产率合成二芳基硫醚.

关键词: 偶联反应, 硫酚, 芳基硼酸, 1,10-菲啰啉, 醋酸铜

Baes-free Cu(II)-catalyzed coupling reaction of arylboronic acid and thiols was described. After optimization of reaction conditions, such as solvents, reaction temperatures, copper salts and ligands, the results show that some biarylsulfides were synthesized in good yields using 1,10-phenanthroline-Cu(OAc)2·H2O as catalyst, DMSO/H2O (V: V=1:1) as solvent, under air atmosphere at 60℃.

Key words: coupling reaction, thiol, arylboronic acid, 1,10-phenanthroline, cupric acetate