有机化学 ›› 2022, Vol. 42 ›› Issue (6): 1626-1639.DOI: 10.6023/cjoc202201028 上一篇    下一篇

综述与进展

羧酸酯合成酮类化合物的研究进展

易文静a,b, 孙威b, 胡信全a, 刘超b,*(), 靳立群a,b,*()   

  1. a 浙江工业大学化学工程学院 杭州 310014
    b 中国科学院兰州化学物理研究所 羰基合成与选择氧化国家重点实验室 兰州 730000
  • 收稿日期:2022-01-19 修回日期:2022-03-08 发布日期:2022-03-21
  • 通讯作者: 刘超, 靳立群
  • 基金资助:
    国家自然科学基金(21972125); 国家自然科学基金(22022113); 国家自然科学基金(21872156); 国家自然科学基金(21773210); 浙江省属高校基本科研业务费(RF-B2019005)

Recent Advance of Ketones Synthesis from Carboxylic Esters

Wenjing Yia,b, Wei Sunb, Xinquan Hua, Chao Liub(), Liqun Jina,b()   

  1. a College of Chemical Engineering, Zhejiang University of Technology, Hangzhou 310014
    b State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics,Chinese Academy of Sciences, Lanzhou 730000
  • Received:2022-01-19 Revised:2022-03-08 Published:2022-03-21
  • Contact: Chao Liu, Liqun Jin
  • Supported by:
    National Natural Science Foundation of China(21972125); National Natural Science Foundation of China(22022113); National Natural Science Foundation of China(21872156); National Natural Science Foundation of China(21773210); Fundamental Research Funds for the Provincial University of Zhejiang(RF-B2019005)

羧酸酯来源广泛, 廉价易得, 其转化受到广泛关注. 酮是一类重要的合成中间体, 可用于合成具有生物活性的复杂药物分子和功能材料. 近二十年来, 羧酸酯合成酮的研究工作取得了重要进展, 主要对近年来羧酸酯转化为酮类化合物的方法进行了综述.

关键词: 酮类化合物, 羧酸酯, 官能团转化

Carboxylic esters are widely obtained, low-cost and readily available. Their conversions have attracted widespread attention. Ketones are important synthetic intermediates, which can be used to synthesize complicated drug molecules and functional materials with biological activity. In recent twenty years, great progress has been made in the synthesis of ketones from carboxylic esters. This review mainly covers the methods of converting carboxylic esters into ketones in recent years.

Key words: ketones, carboxylic esters, functionalization