有机化学 ›› 2022, Vol. 42 ›› Issue (6): 1640-1650.DOI: 10.6023/cjoc202112009 上一篇    下一篇

综述与进展

聚集诱导发光(AIE)和激发态分子内质子转移(ESIPT)结构融合的反应型荧光探针的研究进展

郭钺甜, 潘永鑫, 汤立军*()   

  1. 渤海大学化学与材料工程学院 辽宁锦州 121013
  • 收稿日期:2021-12-04 修回日期:2022-01-23 发布日期:2022-02-17
  • 通讯作者: 汤立军
  • 基金资助:
    国家自然科学基金(21878023); 国家自然科学基金(U1608222); 辽宁省特聘教授支持计划资助项目.

Progresses in Reactive Fluorescent Probes with Fused Aggregation- Induced Emission (AIE) and Excited State Intramolecular Proton Transfer (ESIPT) Structures

Yuetian Guo, Yongxin Pan, Lijun Tang()   

  1. College of Chemistry and Materials Engineering, Bohai University, Jinzhou, Liaoning 121013
  • Received:2021-12-04 Revised:2022-01-23 Published:2022-02-17
  • Contact: Lijun Tang
  • Supported by:
    National Natural Science Foundation of China(21878023); National Natural Science Foundation of China(U1608222); Program for Distinguished Professor of Liaoning Province.

兼具激发态分子内质子转移(ESIPT)和聚集诱导发光(AIE)性质的反应型荧光探针, 因其具有较好的生物相容性、良好的传感性能、较大的斯托克斯位移以及较高的荧光量子效率等优点, 在近几年来被广泛应用于检测各种阴离子、金属阳离子和生物分子中. 简要总结了结构简单, 既是AIE结构模块又是ESIPT结构模块的苯并噻唑、水杨醛席夫碱、肼二腙、查尔酮荧光团等反应型荧光探针的研究进展, 并对相关研究进行了总结和展望.

关键词: 激发态分子内质子转移(ESIPT), 聚集诱导发光(AIE), 荧光探针, 反应型识别

Reactive fluorescent probes with the features of excited state intramolecular proton transfer (ESIPT) and aggregation-induced emission (AIE) have been widely used in the detection of various anions, metal cations and biomolecules in recent years, because they have some advantages including good biocompatibility, good sensing performance, a large Stokes shift, and as well high fluorescence quantum efficiency. The progress in reactive fluorescent probes that are structural simple and have the combined structures of AIE and ESIPT is briefly summarized, and the probes are divided into several types such as benzothiazole, salicylaldehyde Schiff base, hydrazine dihydrazone, chalcone fluorophore, etc. The related researches are discussed and prospected.

Key words: excited state intramolecular proton transfer (ESIPT), aggregation-induced emission (AIE), fluorescent probe, reaction-based recognition