有机化学 ›› 1988, Vol. 8 ›› Issue (6): 481-486.    下一篇

研究论文

格氏试剂与酮反应的一个重要途径: 单电子转移

龚跃法;赵成学   

  1. 中国科学院上海有机化学研究所
  • 发布日期:1988-12-25

A significant pathway for the reactions between Grignard reagents and ketones: Single electron transfer process

GONG YUEFA;ZHAO CHENGXUE   

  • Published:1988-12-25

阐述了格氏试剂和酮的性质影响反应的一般规律, 介绍了普遍接受的格氏试剂与酮反应的机理. 讨论了溶剂及微量过渡金属对反应的影响.

关键词: 反应机理, 酮, 电子跃迁, 格氏试剂

A review with 24 refs. The generally accepted mechanisms for the Grignard reactions of ketones are described. Evidences supporting the single electron transfer (SET) process in some of the reactions under certain conditions are presented. Some main factors, including structure of reactants, nature of solvents and effect of transition-metal impurities, which might affect the course and mechanism (ionic and/or SET) of the reactions are also discussed.6

Key words: REACTION MECHANISM, KETONE, ELECTRON TRANSITION, GRIGNARD REAGENT

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