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有机化学
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有机化学 ›› 1994, Vol. 14 ›› Issue (4): 386-389. 上一篇    下一篇

研究论文

2-芳酰氨基-5-苄基-1,3,4-噻二唑上亚甲基与4-二甲氨基苯甲醛加成反应

冯小明;陈荣;张智波   

  1. 中国科学院成都有机化学研究所;西南师范大学化学系
  • 发布日期:1994-08-25

Studies of nucleophilic addition reaction of 2-aroylamino- 5-benzyl-1,3,4-thiadiazole with 4-dimethylaminobenzaldehyde

FENG XIAOMING;CHEN RONG   

  • Published:1994-08-25

本文报道了2-芳酰氨基-5-苄基-1,3,4-噻二唑(1a～l)与4-二甲氨基甲醛在EtONa/EtOH体系中反应得到12种新的2-芳酰氨基-5-[1'-苯基-2'-羟基(4''-二甲氨基苯乙基)]-1,3,4-噻二唑(2a～l) .

关键词: 苯甲醛 P, 加成反应, 噻二唑 P

Twelve new 2-aroylamino-5-[1'-phenyl-2'-hydroxy (4''- dimethylaminophenylethyl) ]-1,3,4-thiadiazoles 2a-l were obtained by nucleophilic addition of benzyl carbanion of 2-aroylamino-5-benzyl-1,3,4-thiadiazoles 1a-l with 4-dimethyl- aminobenzaldehyde in EtONa / EtOH solution.

Key words: ADDITION REACTION, BENZALDEHYDE P, THIADIAZOLE P

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