关键词: 磷脂酶, 血小板, 磷脂酰胆碱, 抗肿瘤药, 生物活性, 酶抑制剂, 活化, 生理生化特性, 抗真菌药, 因子

Phosphatidylcholines and their analogs, the functional building block of the membrane, are recently found to mediate multiple physiological and pathological processes. Besides acting as the phopholipase inhibitor and platelet activating factor, phospholipids exhibit the membrane-directing biological activities, e.g. antineoplastic cytotoxicity, potential anti-AIDS agent and antifungal activity. So the phospholipid analogs represent a new class of potent biologically active compounds with a wide range of desirable pharmacological effects.

Key words: PHOSPHOLIPASE, PHOSPHATIDYL CHOLINE, PLATELET, PHYSICOCHEMICAL CHARACTERISTICS, ANTITUMOR DRUGS, ACTIVATION, ENZYME INHIBITOR, FACTOR, ANTIFUNGAL AGENTS, BIOLOGICAL ACTIVITY