有机化学 ›› 2023, Vol. 43 ›› Issue (9): 3119-3134.DOI: 10.6023/cjoc202302009 上一篇    下一篇

综述与进展

碳酸亚乙烯酯参与C—H键活化反应的研究进展

高晓阳, 翟锐锐, 陈训*(), 王烁今*()   

  1. 海南医学院药学院 海南省热带药用植物研究开发重点实验室 海口 571199
  • 收稿日期:2023-02-09 修回日期:2023-03-22 发布日期:2023-05-05
  • 作者简介: 共同第一作者.
  • 基金资助:
    国家自然科学基金(21901054); 海南省自然科学基金(222RC683)

Recent Progress in C—H Bond Activation Reaction with Vinylene Carbonate

Xiaoyang Gao, Ruirui Zhai, Xun Chen(), Shuojin Wang()   

  1. Hainan Key Laboratory for Research and Development of Tropical Herbs, School of Pharmacy, Hainan Medical University, Haikou 571199
  • Received:2023-02-09 Revised:2023-03-22 Published:2023-05-05
  • Contact: E-mail: chenxun@hainmc.edu.cn;wang.shuojin@hainmc.edu.cn
  • About author: These authors contributed equally to this work.
  • Supported by:
    National Natural Science Foundation of China(21901054); Hainan Provincial Natural Science Foundation(222RC683)

过渡金属催化导向的C—H键活化反应因具有较高的原子经济性和区域选择性, 为一系列多样性的有机分子的制备提供了一种简便有效的合成渠道. 在众多偶联试剂中, 碳酸亚乙烯酯作为一类新颖、多角色的偶联试剂而被广泛应用于C—H键官能团化反应中. 综述了碳酸亚乙烯酯参与C—H键活化反应的研究进展, 并对其发展前景进行了讨论.

关键词: 碳酸亚乙烯酯, 过渡金属催化, C—H键活化

Transition metal-catalyzed directed C—H bond activation reactions have emerged as a simple and powerful strategy for the construction of multifarious organic molecules due to their high atom-economy and regioselectivity. Among various coupling reagents, vinylene carbonate as a novel and multifunctional coupling reagent has been extensively explored in the transition-metal-catalyzed C—H bond functionalization. In this paper, the recent progress on the application of vinylidene carbonate in C—H bond activation reactions is summarized and the prospect of vinylidene carbonate is discussed.

Key words: vinylene carbonate, transition metal-catalysis, C—H bond activation