有机化学 ›› 2000, Vol. 20 ›› Issue (2): 189-194. 上一篇    下一篇

研究论文

8 - 乙烯基嘌呤上的亲核加成和环加成反应

刘福胜;杨锦宗   

  1. 大连理工大学精细化工国家重点实验室
  • 发布日期:2000-04-25

Nucleophilic addition and cycloaddition to 8 - vinylpurine

Liu Fusheng;Yang Jinzong   

  • Published:2000-04-25

研究了8-乙烯基嘌呤与甲醇、苯硫酚和丙二酸二乙酯之间的亲核加成反应以及与环戊二烯之间的环加成反应。合成了8种未见报道的8位取代的嘌呤衍生物,结构均经^1^HNMR、^13^CNMR、^1^H-^1^HNOESY、MS和元素分析确证。

关键词: 嘌呤P, 亲核反应, 加成反应, 环加成反应, 甲醇, 苯硫酚, 丙二酸乙二酯, 环戊二烯, 质子磁共振谱法, 碳13核磁共振谱法, 质谱法

The nucleophilic addition reaction between 8 - vinylpurine and mathanol, benzenethiol or diethylmalonate and the cycloaddition between 8 - vinylpurine and cyclopentadiene has been investigated. A series of 8 - substituted purines which and not been reported before were prepared and characterized by elemental analysis, ^1H NMR, ^13^C NMR, ^1H - ^1H NOESY and MS.

Key words: PURINE P, NUCLEOPHILIC REACTION, ADDITION REACTION, CYCLOADDITION REACTION, METHANOL, BENZENETHIOL, ETHYLENE GLYCOL MALONATE, CYCLOPENTADIENE, PROTON MAGNETIC RESONANCE SPECTROMETRY, C13 NMR SPECTROMETRY, MASS SPECTROGRAPHY

中图分类号: