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有机化学
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有机化学 ›› 2005, Vol. 25 ›› Issue (03): 342-345. 上一篇    

综述与进展

一氧化氮合酶的结构及其催化机理

王斌*,1,2，苏喜生2，张声华1   

  1. (1华中农业大学食品科学技术学院 武汉 430070)
    (2中国人民解放军军事经济学院营养与食品研究所 武汉 430035)
  • 收稿日期:2004-03-22 修回日期:2004-09-22 发布日期:2005-02-28
  • 通讯作者: 王斌

Structure of Nitric Oxide Synthase and Its Catalytic Mechanism

WANG Bin*,1,2,SU Xi-Sheng2,ZHANG Sheng-Hua1   

  1. (1 College of Food Science and Technology, Huazhong Agriculture University, Wuhan 430070)
    (2 Institute of Nutrition and Food, College of Military Economics, Wuhan 430035)
  • Received:2004-03-22 Revised:2004-09-22 Published:2005-02-28
  • Contact: WANG Bin

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5241

被引次数

50

综述了一氧化氮合酶的结构、功能和催化路径, 讨论了诱导型一氧化氮合酶的结构和功能的关系以及加氧氧化的机理.

关键词: 结构, 功能, 催化机理, 一氧化氮合酶, L-精氨酸

This article reviews the development on studies of the structure, function and catalytic pathway of nitric oxide synthase (NOS). The structure-function relationship and oxygenation mechanism of the iNOS were discussed.

Key words: catalytic mechanism, structure, function, nitric oxide synthase