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有机化学
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有机化学 ›› 2005, Vol. 25 ›› Issue (04): 458-461. 上一篇    下一篇

研究简报

Merrifield树脂负载的膦钯催化剂制备及其在Suzuki反应中的应用

徐宁，王全瑞*，陶凤岗   

  1. (复旦大学化学系 上海200433)
  • 收稿日期:2004-08-16 修回日期:2004-11-02 发布日期:2005-03-30
  • 通讯作者: 王全瑞

Preparation of Merrifield Resin-supported Diphenylphosphinobiph- enyl Palladium Catalyst and Its Application to Suzuki Reactions

XU Ning,WANG Quan-Rui*,TAO Feng-Gang   

  1. (Department of Chemistry, Fudan University, Shanghai 200433)
  • Received:2004-08-16 Revised:2004-11-02 Published:2005-03-30
  • Contact: WANG Quan-Rui

PDF

1585

被引次数

37

合成了一种Merrifield树脂负载的芳基膦钯催化剂, 并将其应用于催化Suzuki反应. 结果表明, 该催化剂对碘代芳烃和溴代芳烃与苯硼酸的Suzuki反应显示出较好的催化效果, 得到相应的联苯. 催化剂循环使用五次, 活性无显著下降.

关键词: 固载化, 催化, Suzuki偶联, 钯

The Merrifield resin-supported diphenylphosphinobiphenyl ligand via an ether linkage was successfully prepared. Complexation with allylpalladium chloride dimer afforded the polymer-supported catalyst, which exhibits good activities for the Suzuki cross-coupling reactions. A range of aryl iodides and bromides can couple with phenylboronic acid to provide the respective biaryls. The resin-bound catalysts can be recycled for five times without obvious decline in activity.

Key words: immobilization, palladium, Suzuki cross-coupling, catalysis