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有机化学
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有机化学 ›› 2006, Vol. 26 ›› Issue (06): 775-782. 上一篇    下一篇

综述与进展

辅酶NAD(P)H模型分子的研究进展

王乃兴*，赵嘉   

  1. (中国科学院理化技术研究所 北京 100101)
  • 收稿日期:2005-07-15 修回日期:2006-11-02 发布日期:2006-05-31
  • 通讯作者: 王乃兴

Progress in Coenzyme NAD(P)H Model Compounds

WANG Nai-Xing*,ZHAO Jia   

  1. (Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100101)
  • Received:2005-07-15 Revised:2006-11-02 Published:2006-05-31
  • Contact: WANG Nai-Xing

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1247

被引次数

16

辅酶NAD(P)H在生物体内起着重要的调节作用, 已引起了有机化学工作者极大的兴趣, 尤其是在还原反应的立体选择性上, 人们已经开展了大量的研究工作. 讨论了NAD(P)H模型分子进行立体专一性还原反应的影响因素, 并对NAD(P)H模型分子的研究工作做了总结.

关键词: NAD(P)H, 辅酶, 立体选择性, 还原

NAD(P)H could play an important role in the living systems, which has stimulated a great deal of interest in the field of bioorganic chemistry. A large number of NAD(P)H model compouds have been developed for the study on the stereoselective reduction. Herein, the factors on the stereoselective reduction of NAD(P)H model compounds are discussed and the progress in coenzyme NAD(P)H model compounds is summarized.

Key words: reduction, coenzyme, stereoselectivity, NAD(P)H