有机化学 ›› 2006, Vol. 26 ›› Issue (9): 1173-1191. 上一篇    下一篇

综述与进展

氮杂环丙化反应研究的新近进展

程习星a,张玉清a,何兰b,陈庆华*,b   

  1. (a河南科技大学化工与制药学院 洛阳 471003)
    (b北京师范大学化学系 北京 100875)
  • 收稿日期:2005-07-18 修回日期:1900-01-01 发布日期:2006-09-11
  • 通讯作者: 陈庆华

Recent Progress in the Study of Aziridination Reaction

CHENG Xi-Xinga,ZHANG Yu-Qinga,HE Lanb,CHEN Qing-Hua*,b   

  1. (a College of Chemical Engineering and Pharmaceutics, Henan University of Science and Technol-ogy, Luoyang 471003)
    (b Department of Chemistry, Beijing Normal Univer-sity, Beijing 100875)
  • Received:2005-07-18 Revised:1900-01-01 Published:2006-09-11
  • Contact: CHEN Qing-Hua

综述了近几年氮杂环丙化反应研究工作的进展, 重点介绍了乃春与烯烃的转换, 卡宾与N=C的转换以及不同反应底物官能团转换的合成策略.

关键词: 合成策略, 不对称合成, 生物活性, 氮杂环丙化反应

This article reviews the recent progress in the study of aziridination reaction using different synthetic strategy, focusing on aziridination via nitrene transfer to olefins, carbene addition to C=N double bonds and the functional group transformation from different reaction substrates.

Key words: synthetic strategy, asymmetric synthesis, biologic activity, aziridination