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有机化学
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有机化学 ›› 2007, Vol. 27 ›› Issue (02): 272-275. 上一篇    下一篇

研究简报

Pd(II)催化下苄基溴化锌或烯丙基碘化锌与芳香醛的加成反应

门秀琴，孟团结，王进贤*，辛丽   

  1. (西北师范大学化学化工学院 兰州 730070)
  • 收稿日期:2005-10-17 修回日期:2006-07-14 发布日期:2007-01-30
  • 通讯作者: 王进贤

Pd(II) Catalyzed Addtion Reaction of Benzylzinc Bromides or Allylzinc Iodines with Aromatic Aldehydes

MEN Xiu-Qin, MENG Tuan-Jie, WANG Jin-Xian*, XIN Li   

  1. (College of Chemistry and Chemical Engineering, Northwest Normal University, Lanzhou 730070)
  • Received:2005-10-17 Revised:2006-07-14 Published:2007-01-30
  • Contact: WANG Jin-Xian

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1425

被引次数

3

在[PdCl2(PPh3)2]催化下, 有机卤化锌试剂与芳香醛顺利地发生反应得到了较高产率的1,2-加成产物. 此方法避免了CuCN/2LiCl的使用, 为通过有机卤化锌试剂合成芳基取代的仲醇类化合物提供了一条简便的途径.

关键词: Pd(II)催化, 加成反应, 有机卤化锌, 芳香醛

The addition reaction of organozinc halides with aromatic aldehydes occurs readily catalyzed by amount [PdCl2(PPh3)2] to afford 1,2-addtion products in high yields. This method avoided the use of toxic CuCN/2LiCl and provided a simple way for the synthesis of aryl substituted secondary alcohols.

Key words: Pd(II) catalyzed, aromatic aldehyde, addition reaction, organozinc halide