有机化学 ›› 2009, Vol. 29 ›› Issue (02): 283-288. 上一篇    下一篇

研究简报

一氧化氮氧化芳构化1,3,5-三取代吡唑啉

伍文韬 ; 李 锐 ; 刘 强; 吴隆民*   

  1. (兰州大学功能有机分子化学国家重点实验室 兰州 73000)
  • 收稿日期:2007-11-28 修回日期:2008-08-25 发布日期:2009-02-20
  • 通讯作者: 吴隆民

Oxidative Aromatization of 1,3,5-Trisubstituted Pyrazolines with Nitric Oxide

Wu, Wentao; Li, Rui ; Liu, Qiang ; Wu, Longmin*   

  1. (State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 730000)
  • Received:2007-11-28 Revised:2008-08-25 Published:2009-02-20
  • Contact: Wu, Longmin

室温下, 一氧化氮氧化芳构化1,3,5-三取代吡唑啉, 高产率地得到了相应的产物1,3,5-三取代吡唑. 产物结构通过各种谱图数据确定. 该反应具有反应条件温和、操作简便易行以及产率高等优点.

关键词: 一氧化氮, 氧化芳构化, 吡唑啉, 吡唑

A series of 1,3,5-trisubstituted pyrazolines were highly efficiently oxidized to corresponding pyrazoles with nitric oxide at room temperature in CH2Cl2. The structure of products was characterized by various spectroscopic data. This entry offers several advantages like simple handlings, mild reaction conditions and high yields of products.

Key words: oxidative aromatization, nitric oxide, pyrazoline, pyrazole