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有机化学
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有机化学 ›› 2010, Vol. 30 ›› Issue (12): 1801-1810.    下一篇

综述与进展

天然活性吡咯烷-2,4-二酮类化合物研究进展

梁英*，柯少勇，王开梅，杨自文   

  1. 湖北省农业科学院 湖北省生物农药工程研究中心 武汉 430064
  • 收稿日期:2010-01-14 修回日期:2010-05-05 发布日期:2010-06-03
  • 通讯作者: 梁英 E-mail:ly.liang8@gmail.com

Progress in the Studies on Natural Bioactive Pyrrolidine-2,4-diones

LIANG Ying, KE Shao-Yong, WANG Kai-Mei, YANG Zi-Wen   

  1. Hubei Biopesticide Engineering Research Center, Hubei Academy of Agricultural Science, Wuhan 430064
  • Received:2010-01-14 Revised:2010-05-05 Published:2010-06-03
  • Contact: LIANG Ying E-mail:ly.liang8@gmail.com

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被引次数

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吡咯烷-2,4-二酮类化合物广泛存在于陆上及海洋生物中, 其复杂多变的分子结构和广谱独特的生物活性引起人们的极大关注. 结合本研究组在这一邻域的工作综述了天然吡咯烷-2,4-二酮类化合物的结构、生物活性, 重点介绍此类化合物的全合成等方面的新进展.

关键词: 吡咯烷-2,4-二酮, 生物活性, 全合成, 进展

The naturally occurring pyrrolidine-2,4-dione (tetramic acid) derivatives originating from a variety of marine and terrestrial species have attracted a great deal of interest due to their broad-spectrum biological activities and challenging structural complexity. In this paper, recent advances in the structures, biological activities especially total synthesis of natural pyrrolidine-2,4-dione derivatives are reviewed.

Key words: tetramic acid, biological activity, total synthesis, progress