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有机化学
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有机化学 ›› 2011, Vol. 31 ›› Issue (08): 1319-1323. 上一篇    下一篇

学术动态

钯催化的交叉偶联反应——2010年诺贝尔化学奖获奖工作介绍

王乃兴   

  1. (中国科学院理化技术研究所 北京 100190)
  • 收稿日期:2010-12-09 修回日期:2011-03-10 发布日期:2011-03-10
  • 通讯作者: 王乃兴 E-mail:nxwang@mail.ipc.ac.cn,naixingwang@hotmail.com

Palladium-Catalyzed Cross-Coupling Reactions— Introduction of Nobel Prize in Chemistry in 2010

WANG Nai-Xing   

  1. (Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190)
  • Received:2010-12-09 Revised:2011-03-10 Published:2011-03-10

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2717

被引次数

42 | 7

钯催化的交叉偶联反应是非常实用的合成新方法. 文章给出了Heck反应、Negishi反应和Suzuki反应的概念, 对其反应机理作了详细的说明, 并对其在复杂化合物和天然产物全合成中的应用作了评价.

关键词: 钯催化, Heck反应, Negishi反应, Suzuki反应

Palladium-catalyzed cross-coupling reactions provide chemists with a more precise and efficient new methodologies. The concepts of the Heck reaction and Negishi reaction as well as Suzuki reaction are given, the reaction mechanisms are proposed, and applications of these reactions in the total synthesis of natural products are commented.

Key words: palladium-catalyzed, Heck reaction, Negishi reaction, Suzuki reaction