有机化学 ›› 2009, Vol. 29 ›› Issue (08): 1175-1181. 上一篇    下一篇

综述与进展

有机硼酸类催化剂在有机合成中的应用

吴记勇 ; 方 浩*; 徐文方   

  1. (山东大学药物化学研究所 济南 250012)
  • 收稿日期:2008-10-08 修回日期:2008-12-23 发布日期:2009-08-30
  • 通讯作者: 方 浩

Application Progress of Boronic Acid Catalyst in Organic Synthesis

Wu, Jiyong; Fang, Hao*; Xu, Wenfang   

  1. (Department of Medicinal Chemistry, Shandong University, Jinan 250012)
  • Received:2008-10-08 Revised:2008-12-23 Published:2009-08-30
  • Contact: Fang, Hao

综述了有机硼酸类作为催化剂应用于有机合成反应中的最新研究进展, 重点介绍了所发现的各种有机硼酸催化剂在缩合反应、羧酸还原反应、Diels-Alder反应中的催化活性以及反应机理. 硼酸催化剂因具有催化效率高、反应条件温和、可重复使用等优点, 必将在有机合成催化领域中得到更广泛的应用.

关键词: 有机硼酸, 催化剂, 有机合成

The latest applications of boronic acids as catalyst to organic synthesis are reviewed, focusing on the catalytic activities and reaction mechanism of different catalysts discovered in condensation reaction, carboxylic acid reduction reaction, and Diels-Alder reaction. Boronic acids as catalyst will be widely used in organic synthesis for its effective activity, mild conditions and many times reusable.

Key words: organic synthesis, catalyst, boronic acid