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有机化学
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有机化学 ›› 2005, Vol. 25 ›› Issue (11): 1459-1461. 上一篇    下一篇

研究简报

手性多噁唑啉的一步合成方法

李伟杰*,1，许遵乐2   

  1. (1汕头大学多学科研究中心 汕头 515063)
    (2中山大学化学与化学工程学院 广州 510275)
  • 收稿日期:2005-04-05 修回日期:2005-05-18 发布日期:2005-10-30
  • 通讯作者: 李伟杰

Synthesis of Multioxazolines in One Step

LI Wei-Jie*,1,XU Zun-Le2   

  1. (1 Multidisciplinary Research Center, Shantou University, Shantou 515063)
    (2 School of Chemistry and Chemical Engineering, Zhongshan University, Guangzhou 510275)
  • Received:2005-04-05 Revised:2005-05-18 Published:2005-10-30
  • Contact: LI Wei-Jie

PDF

1267

被引次数

17

尽管已报道了多种结构类型的手性单或双噁唑啉, 但手性多噁唑啉的合成及其应用的文献报道比较少. 本工作以多元羧酸为原料, 与手性2-氨基-1-丁醇经一步反应合成了8个手性多噁唑啉, 产率为89%～98%, 其结构经1 H NMR谱、IR谱、MS谱和元素分析确证.

关键词: 多噁唑啉, 手性试剂, 合成

Although quite of varieties of mono- or bis-oxazolines have been reported, multi-oxazolines were seldom recorded in literatures. Eight chiral polyoxazolines were synthesized in 89%～98% yields from multiple acids and chiral 2-amino-1-butanol in one step, and their chemical structures were determined by 1H NMR, IR, MS spectra and elemental analysis.

Key words: chiral reagent, synthesis, multioxazoline