有机化学 ›› 1997, Vol. 17 ›› Issue (3): 247-251. 上一篇    下一篇

研究论文

异色满酮-4及其衍生物的合成IX异香豆素并杂环化合物的合成

周健民;王进军;于林超;王广铨;韩光范;姜贵吉   

  1. 温州医学院化学研究室;吉林化工学院环境化工系;吉林医学院检验系;延边大学化学系
  • 发布日期:1997-06-25

Synthesis of isocoumarin-fused heterocyclic compounds

ZHOU JIANMIN;WANG JINJUN;YU LINCHAO;WANG GUANGQUAN;HAN GUANGFAN;JIANG GUIJI   

  • Published:1997-06-25

本文通过3, 4-二氢异苯并吡喃酮-4和其β-二酮衍生物的缩合反应, 合成出3, 4-二氢异苯并吡喃并吲哚、并喹啉、并吡唑和并嘧啶类化合物, 并进一步氧化成标题化合物。所合成的新化合物均经核磁共振光谱红外光谱及元素分析证明其分子结构。

关键词: 色满酮, 异香豆素, 苯并吡唑, 缩合反应, 苯并嘧啶, 苯并吲哚, 苯并吡喃, 红外分光光度法, 核磁共振谱法, 元素分析

In this paper, a series of 3, 4-dihydro-isobenzopyran-fused heterocyclic compounds (2a-6b) were synthesized from 3, 4-dihydro-isobenzopyranone-4 and its β-diketon derivatives. Oxidation of these heterocyclic compounds by chromium trioxide furnished isocoumarin-fused heterocyclic compounds (7a-10b). The structures of all these compounds were characterized by elemental analysis, IR and 1HNMR spectra.

Key words: INFRARED SPECTROPHOTOMETRY, ISOCOUMARIN, BENZOPYRAN, ELEMENTAL ANALYSIS, NMR SPECTROMETRY, CONDENSATION REACTION

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