有机化学 ›› 2008, Vol. 28 ›› Issue (06): 1097-1101. 上一篇    下一篇

研究简报

二醋酸碘苯在碘和三苯基膦作用下酰化醇、酚和胺

周其忠*,何春林,陈振初   

  1. (浙江大学化学系 杭州 310027)
  • 收稿日期:2007-08-12 修回日期:2007-12-05 发布日期:2008-06-26
  • 通讯作者: 周其忠

Novel Acylation of Alcohols, Phenols and Amines with Diacetoxyio-dobenzene in the Presence of Iodine and Triphenylphosphine

ZHOU Qi-Zhong*, HE Chun-Lin, CHEN Zhen-Chu   

  1. (<i><sup>a</sup></i> <I>Department of Chemistry</i>, <I>Zhejiang University</i>, <I>Hangzhou 310027</i>)
  • Received:2007-08-12 Revised:2007-12-05 Published:2008-06-26
  • Contact: ZHOU Qi-Zhong

二醋酸碘苯与碘在三苯基膦作用下形成的乙酰氧鏻中间体在三乙胺的催化下与醇、酚、胺一锅法反应以中等和高产率得到酯和酰胺.

关键词: 二醋酸碘苯, 酰化, 酯, 乙酰氧鏻, 酰胺

Various esters and amides were synthesized in one pot in moderate to excellent yields by the reaction of alcohols, phenols or amines with acyloxyphosphonium intermediate generated from diacetoxyiodobenzene and iodine in the presence of triphenylphosphine followed by treatment with triethylamine.

Key words: ester, acylation, amide, acyloxyphosphonium, diacetoxyiodobenzene