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有机化学
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有机化学 ›› 2005, Vol. 25 ›› Issue (06): 734-737. 上一篇    下一篇

研究简报

溴代羟基二苯醚的合成及抑菌活性研究

王玉良1，马梦林1,2，傅容1，陈淑华*,1，杨志荣3，侯若桐3   

  1. (1四川大学化学学院 成都 610064)
    (2西华大学化学系 成都 611930)
    (3四川大学生命科学学院 成都 610064)
  • 收稿日期:2004-08-19 修回日期:2004-12-23 发布日期:2005-05-30
  • 通讯作者: 陈淑华

Study on the Synthesis and Bactericidal Activities of New Brominated Hydroxy Diphenyl Ether

WANG Yu-Liang1MA Meng-Lin1,2FU Rong1CHEN Shu-Hua*1
YANG Zhi-Rong3HOU Ruo-Tong3   

  1. (1 College of Chemistry, Sichuan University, Chengdu 610064)
    (2 Department of Chemistry, Xihua University, Chengdu 611930)
    (3 College of Life Science, Sichuan University, Chengdu 610064)
  • Received:2004-08-19 Revised:2004-12-23 Published:2005-05-30
  • Contact: CHEN Shu-Hua

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1508

被引次数

19

模拟天然溴代羟基二苯醚的结构, 设计并合成了7个溴代羟基二苯醚化合物, 所有这些新化合物的结构均经元素分析, 1H NMR, MS和IR所证实. 选择8种有害菌对合成的溴代羟基二苯醚进行了抑菌活性检测, 证实它们对所测试菌种具有优良的抑制效果.

关键词: 溴代羟基二苯醚, 合成, 抑菌活性

Seven brominated hydroxy diphenyl ethers have been designed and synthesized. Their structures have been confirmed by 1H NMR, MS, IR spectra and elemental analyses. The bactericidal test showed that these compounds possess good antimicrobial activity toward the tested bacterium.

Key words: brominated hydroxy diphenyl ether, antimicrobial activity, synthesis