有机化学 ›› 2012, Vol. 32 ›› Issue (06): 1112-1115.DOI: 10.6023/cjoc1202054 上一篇    下一篇

研究简报

微波辐射下一步合成4-芳基-2,6-二(3,3'-香豆素基)吡啶衍生物

周建峰, 娄风文, 孙小军, 安礼涛, 支三军, 霍娟娟, 郑丽, 王星帅   

  1. 淮阴师范学院化学化工学院, 江苏省低维材料化学重点建设实验室, 淮安 223300
  • 收稿日期:2012-02-05 修回日期:2012-03-22 发布日期:2012-04-10
  • 通讯作者: 周建峰 E-mail:zhoujf@sohu.com
  • 基金资助:
    江苏省低维材料化学重点建设实验室开放基金(JSKC11101)资助项目.

One-Pot Synthesis of 3,3'-(4-arylpyridine-2,6-diyl)-bis (2H-chromen-2-one) Derviatives under Microwave Irradiation

Zhou, Jianfeng Lou, Fengwen Sun, Xiaojun An, Litao Zhi, Sanjun Huo, Juanjuan Zheng, Li Wang, Xingshuai   

  1. School of Chemistry and Chemical Engineering, Jiangsu Key Laboratory for Chemistry of Low-Dimensional Materials, Huaiyin Normal University, Huai’an 223300
  • Received:2012-02-05 Revised:2012-03-22 Published:2012-04-10
  • Supported by:
    Project supported by Jiangsu Key Laboratory for Chemistry of Low-Dimensional Materials (JSKC11101 ).

3-乙酰基香豆素、芳醛和醋酸铵在醋酸溶剂中经微波辐射, 一步合成了4-芳基-2,6-二(3,3'-香豆素基)吡啶衍生物,反应在5~8 分钟内完成,产率60~86%,具有反应时间短、操作简便和环境友好等优点.所以产物经红外光谱、氢谱、质谱和元素分析表征.

关键词: 3-乙酰基香豆素, 芳醛, 吡啶衍生物, 微波辐射

A series of 3,3'-(4-arylpyridine-2,6-diyl)bis(2H-chromen-2-one) derviatives were synthesized by the one-pot three-component reaction of 3-acetyl coumarin, aromatic aldehydes, and ammonium acetate in acetic acid under microwave irradiation. The reactions were completed in 5~8 min with 60%~86% yields, and the procedure has the advantages of short reaction time, easy work-up and environmental begin. Their structures were confirmed by 1H NMR, IR, MS techniques and elemental analysis.

Key words: pyridine derivatives, 3-acetylcoumarin, aromatic aldehyde, microwave irradiation