有机化学 ›› 2020, Vol. 40 ›› Issue (12): 4071-4086.DOI: 10.6023/cjoc202004047 上一篇    下一篇

综述与进展

喹啉氮氧化物的功能化反应研究进展

董道青a, 孙媛媛a, 李光辉a, 杨欢a, 王祖利a, 徐鑫明b   

  1. a 青岛农业大学化学与药学院 山东青岛 266109;
    b 烟台大学化学化工学院 山东烟台 264005
  • 收稿日期:2020-04-29 修回日期:2020-06-30 发布日期:2020-07-17
  • 通讯作者: 王祖利 E-mail:wangzulichem@163.com
  • 基金资助:
    国家自然科学基金(No.21772107)和山东省重点研发计划(No.2019GSF108017)资助项目.

Recent Progress in the Functionalization of Quinoline N-Oxide

Dong Daoqinga, Sun Yuanyuana, Li Guanghuia, Yang Huana, Wang Zulia, Xu Xinmingb   

  1. a College of Chemistry and Pharmaceutical Sciences, Qingdao Agricultural University, Qingdao, Shandong 266109;
    b College of Chemistry and Chemical Engineering, Yantai University, Yantai, Shandong 264005
  • Received:2020-04-29 Revised:2020-06-30 Published:2020-07-17
  • Supported by:
    Project supported by the National Natural Science Foundation of China (No. 21772107) and the Key Research and Development Plan of Shandong Province (No. 2019GSF108017).

喹啉氮氧化物廉价易得,被广泛应用于有机合成.综述了近些年喹啉氮氧化物的C(2)与C(8)位的功能化反应与反应机理,为今后喹啉氮氧化物的反应提供参考.

关键词: 喹啉氮氧化物, 含氮化合物, 功能化反应, 反应机理

Owning to their low cost and readily available, quinoline N-oxides are widely used in organic synthesis. The functionalization reactions of C(2) and C(8) position of quinoline N-oxides and the reaction mechanisms of these reactions are summaried. It will be helpful for the reaction of quinoline N-oxide in the future.

Key words: quinolone N-oxide, nitrogen compounds, functionalization, reaction mechanism