有机化学 ›› 2022, Vol. 42 ›› Issue (1): 266-276.DOI: 10.6023/cjoc202104037 上一篇    下一篇

研究论文

可见光促进钯催化C—H键胺化反应合成咔唑醌衍生物的研究

韩阳, 姜为超, 张靖, 彭进松*(), 陈春霞*()   

  1. 东北林业大学化学化工与资源利用学院 哈尔滨 150040
  • 收稿日期:2021-04-17 修回日期:2021-07-14 发布日期:2021-09-02
  • 通讯作者: 彭进松, 陈春霞
  • 作者简介:
    † 共同第一作者.
  • 基金资助:
    黑龙江省自然科学基金(ZD2021C001); 中央高校基本科研基金(2572019CG06)

Visible-Light-Promoted Palladium-Catalyzed C—H Amination for the Synthesis of Carbazolequinones

Yang Han, Weichao Jiang, Jing Zhang, Jinsong Peng(), Chunxia Chen()   

  1. College of Chemistry, Chemical Engineering and Resource Utilization, Northeast Forestry University, Harbin 150040
  • Received:2021-04-17 Revised:2021-07-14 Published:2021-09-02
  • Contact: Jinsong Peng, Chunxia Chen
  • About author:
    † These authors contributed equally to this work.
  • Supported by:
    Natural Science Foundation of Heilongjiang Province(ZD2021C001); Fundamental Research Funds for the Central Universities(2572019CG06)

以2-氨基-3-芳基萘-1,4-二酮为底物, 发展了一类可见光/钯催化的分子内C—H键氧化胺化反应. 以氧气作为氧化剂及醋酸钯作为催化剂, 在蓝色LED光照射下, 2-氨基-3-芳基萘-1,4-二酮底物在室温下被转化为咔唑醌衍生物, 反应具有良好的产率、官能团耐受性和优异的区域选择性.

关键词: 光促进, 钯催化, 碳-氢键胺化, 咔唑醌

An intramolecular palladium-catalyzed cross-dehydrogenative C—H amination under blue LED irradiation at room temperature was developed. With oxygen as the external oxidant, a broad range of functional groups was compatible with the aromatic C—H amination of 2-amino-3-arylnaphthalene-1,4-diones, and diverse carbazolequinones can be obtained with good yields and excellent regioselectivity.

Key words: light-promoted, palladium-catalyzed, C—H amination, carbazolequinones