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有机化学
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有机化学 ›› 2004, Vol. 24 ›› Issue (4): 396-398. 上一篇    下一篇

研究论文

二茂铁甲醛与含活性亚甲基化合物的水相反应研究

白银娟*, 路军, 王振军, 苏玉婵, 史真   

  1. 西北大学化学系 西安 710069
  • 收稿日期:2003-06-09 修回日期:2003-08-26 接受日期:2003-10-14 发布日期:2022-09-19
  • 基金资助:
    陕西省教育厅专项基金(No. 01JK205)资助项目

Reactions of Ferrocenecarboxaldehyde with Compounds Containing Active Methylene Group in Aqueous Solution

BAI, Yin-Juan*, LU, Jun, WANG, Zhen-Jun, SU, Yu-Chan, SHI, Zhen   

  1. Department of Chemistry, Northwest University, Xi'an 710069
  • Received:2003-06-09 Revised:2003-08-26 Accepted:2003-10-14 Published:2022-09-19
  • Contact: *E-mail: baiyinjuan@tom.com

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二茂铁甲醛与具有活性亚甲基的化合物巴比妥酸(2a)、硫代巴比妥酸(2b)、2,2-二甲基-1,3-二口恶烷-4,6-二酮(2c)、1-苯基-3-甲基-5-吡唑啉酮(2d)、 氰乙酸乙酯(2e)、2,4-戊二酮(2f)、环己酮(2g)及环戊酮(2h)在水相中进行缩合反应,高产率简便地得到α-二茂铁亚甲基酮.产物结构经1H NMR, 13C NMR, IR及元素分析进行了表征.

关键词: 二茂铁甲醛, 活性亚甲基, 缩合, 水相反应

Ferrocenylmethylene containing ketones were achievedby the reactions of ferrocenecarboxaldehyde with compoundscontaining active methylene group, such as barbituric acid (2a), thiobarbituric acid (2b), 2,2-dimethyl-1,3-dioxane-4,6-dione (2c), 3-methyl-1-phenyl-2-pyrazoline-5-one (2d), ethyl cyanoacetate (2e), 2,4-pentandione (2f), cyclohexanone (2g) and cyclopentanone (2h) in aqueous solution with good yields. The structures of products were confirmed by 1H NMR, 13C NMR, IR spectra and elemental analysis.

Key words: ferrocenecarboxaldehyde, active methylene group, condensation, aqueous reaction