Synthesis and Biological Activity of 1-Aroyl-3-[4-((2-Cyanoimino-1,3-thiazolidine- 3-yl)methyl)-thiazol-2-yl]Thioureas

doi:10.6023/cjoc1202072

Chin. J. Org. Chem. ›› 2012, Vol. 32 ›› Issue (07): 1327-1331.DOI: 10.6023/cjoc1202072 Previous Articles Next Articles

Notes

1-芳甲酰基-3-[4-((2-氰基亚胺基-1,3-噻唑烷-3-基)甲基)-噻唑-2-基]硫脲的合成及其生物活性研究

戴红^a,b, 苗文科^a, 刘建兵^a, 吴珊珊^a, 秦雪^a, 张欣^a, 方建新^a

a 南开大学元素有机化学国家重点实验室天津 300071;
b 南通大学化学化工学院南通 226019

收稿日期:2012-02-07 修回日期:2012-04-26 发布日期:2012-05-11
通讯作者: 戴红, 方建新 E-mail:daihong_2001@yahoo.com.cn; fjx@nankai.edu.cn
基金资助:
国家自然科学基金(No. 20772068);南通市科技计划(Nos. AS2010005)资助项目.

Synthesis and Biological Activity of 1-Aroyl-3-[4-((2-Cyanoimino-1,3-thiazolidine- 3-yl)methyl)-thiazol-2-yl]Thioureas

Dai Hong^a,b, Miao Wenke^a, Liu Jianbing^a, Wu Shanshan^a, Qin Xue^a, Zhang Xin^a, Fang Jianxin^a

a State Key Laboratory of Elemento-organic Chemistry, Nankai University, Tianjin 300071;
b College of Chemistry and Chemical Engineering, Nantong University, Nantong 226019

Received:2012-02-07 Revised:2012-04-26 Published:2012-05-11
Supported by:
Project supported by the National Natural Science Foundation of China (No. 20772068) and the Science and Technology Project Fund of Nantong City (No. AS2010005).

In order to explore potent pesticide containing heterocycle, fourteen new 1-aroyl-3-[4-((2-cyanoimino-1,3-thiazolidine-3-yl)methyl)-thiazol-2-yl]thiourea compounds were designed and synthesized by introducing the important acylthiourea moiety into the molecular structure of thiazole. Their structures were identified by ¹H NMR spectra and elemental analysis. The preliminary bioassay revealed that some compounds showed certain fungicidal, plant growth regulatory or herbicidal activities.

Key words: thiazole, acylthiourea, synthesis, biological activity

Cite this article

Dai Hong, Miao Wenke, Liu Jianbing, Wu Shanshan, Qin Xue, Zhang Xin, Fang Jianxin. Synthesis and Biological Activity of 1-Aroyl-3-[4-((2-Cyanoimino-1,3-thiazolidine- 3-yl)methyl)-thiazol-2-yl]Thioureas[J]. Chin. J. Org. Chem., 2012, 32(07): 1327-1331.

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1-芳甲酰基-3-[4-((2-氰基亚胺基-1,3-噻唑烷-3-基)甲基)-噻唑-2-基]硫脲的合成及其生物活性研究

Synthesis and Biological Activity of 1-Aroyl-3-[4-((2-Cyanoimino-1,3-thiazolidine- 3-yl)methyl)-thiazol-2-yl]Thioureas

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