Chin. J. Org. Chem. ›› 2019, Vol. 39 ›› Issue (3): 754-760.DOI: 10.6023/cjoc201808027 Previous Articles     Next Articles



和振秀a, 周永云a, 孙蔚青a, 樊瑞峰b, 沈国礼a, 樊保敏a,b   

  1. a 云南民族大学 云南民族大学-香港浸会大学传统天然药物研发联合实验室 昆明 650500;
    b 云南民族大学 民族药资源化学国家民委-教育部重点实验室 昆明 650500
  • 收稿日期:2018-08-23 修回日期:2018-10-09 发布日期:2018-11-12
  • 通讯作者: 周永云, 樊保敏;
  • 基金资助:


Asymmetric Ring Opening Reaction of Oxabenzonorbornadienes with Phenols Promoted by Rhodium/Zinc Complexes

He Zhenxiua, Zhou Yongyuna, Sun Weiqinga, Fan Ruifengb, Shen Guola, Fan Baomina,b   

  1. a Yunnan Minzu University-Hong Kong Baptist University Joint Laboratory of Traditional Natural Medicine, Yunnan Minzu University, Kunming 650500;
    b Key Laboratory of Chemistry in Ethnic Medicinal Resources, Yunnan Minzu University, Kunming 650500
  • Received:2018-08-23 Revised:2018-10-09 Published:2018-11-12
  • Contact: 10.6023/cjoc201808027;
  • Supported by:

    Project supported by the National Natural Science Foundation of China (No. 21572198) and the Applied Basic Research Project of Yunnan Province (No. 2017FA004).

The complex of[Rh(COD) Cl]2 and 2R,4R) -(+) -2,4-bis(diphenylphosphino) pentane was used as an effective catalyst for the asymmetric ring opening reaction of oxabenzonorbornadienes with various phenols by employing ZnI2 as the activator. Under the optimized reaction conditions, high enantioselectivities with good yields could be obtained from a wide scope of oxabenzonorbornadienes and phenols.

Key words: rhodium, oxabenzonorbornadienes, Co-catalysis, symmetric ring opening reaction, Lewis acid