Chinese Journal of Organic Chemistry ›› 2020, Vol. 40 ›› Issue (11): 3697-3713.DOI: 10.6023/cjoc202004045 Previous Articles     Next Articles

Special Issue: 有机光催化虚拟合辑 创刊四十周年专辑


周文俊a,b, 蒋元旭b, 陈亮b, 刘开兴a, 余达刚b   

  1. a 内江师范学院化学化工学院 四川内江 641100;
    b 四川大学化学学院 绿色化学与技术教育部重点实验室 成都 610064
  • 收稿日期:2020-04-28 修回日期:2020-05-21 发布日期:2020-05-29
  • 通讯作者: 周文俊, 余达刚;
  • 基金资助:

Visible-Light Photoredox and Palladium Dual Catalysis in Organic Synthesis

Zhou Wenjuna,b, Jiang Yuanxub, Chen Liangb, Liu Kaixinga, Yu Dagangb   

  1. a College of Chemistry and Chemical Engineering, Neijiang Normal University, Neijiang, Sichuan 641100;
    b Key Laboratory of Green Chemistry&Technology of Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064
  • Received:2020-04-28 Revised:2020-05-21 Published:2020-05-29
  • Supported by:
    Project supported by the National Natural Science Foundation of China (Nos. 21801176, 21772129), the National Basic Research Program of China (973 Program) (No. 2015CB856600), the Sichuan Science and Technology Program (No. 2019YJ0379) and the Open Project of Neijiang Normal University (No. KF10076).

Palladium-catalyzed organic transformations is an important branch of organometallic chemistry. Because it can efficiently construct carbon-carbon bonds and carbon-heteroatom bonds, palladium catalysis has been widely used in synthetic chemistry, material science and pharmaceutical industry. However, some of these reactions suffer from harsh reaction conditions, including high temperature and strong base. On the other hand, the visible-light photoredox catalysis employs the visible light as the energy source to generate highly reactive intermediates and realize many novel transformations, which are rare under the normal thermal reaction conditions, under mild reaction conditions. However, there are also limitations in reaction types and substrate scope in this field. In order to solve such problems in these two fields, organic chemists have merged the visible-light photoredox catalysis and palladium catalysis, realizing a series of novel organic transformations through the electron transfer or energy transfer between photosensitizer and organic palladium complex under mild conditions with high efficiency and selectivity, which has broad substrate scope and great application potential. In these transformations, visible-light photoredox catalysis and palladium catalysis both play their respective roles and cooperate well. The application of visible light photoredox and palladium dual catalysis in organic synthesis is summarized and the future research directions in this field are analyzed, which might help the further development of this field.

Key words: visible-light photoredox catalysis, palladium catalysis, dual catalysis, organic synthesis