Chin. J. Org. Chem. ›› 1990, Vol. 10 ›› Issue (5): 464-470. Previous Articles     Next Articles

Original Articles

光学活性芳族氰醇的合成及其稳定性的研究

童跃进;丁孟贤   

  1. 中国科学院长春应用化学研究所
  • 发布日期:1990-10-25

Synthesis of optically active cyanohydrins and study on their stabilities

TONG YUEJIN;DING MENGXIAN   

  • Published:1990-10-25

Twenty chiral catalysts, among which twelve were prepared or purified in this work, have been used in the asym. synthesis of cyanohydrins from benzaldehyde. The activity and enantioselectivity of these catalysts in the reaction have been observed The optical yields of these asym. reaction varied from zero to about 60%. The investigation on the stability of the cyanohydrins showed that the purified cyanohydrins could be optically stable within a week without apparent decrease of their optical rotation and chem. stable over 5 mo. The mechanism of the reaction and the evaluation of enantioselectivity of the catalysts have also been discussed.

Key words: REACTION MECHANISM, STABILITY, INFRARED SPECTROPHOTOMETRY, ALCOHOL, CYANOGEN COMPOUNDS, NMR SPECTROMETRY, ELEMENTAL ANALYSIS, AROMATIC COMPOUNDS, RACEMIZATION

CLC Number: