2, 6-Di(hydroxymethyl)-pyridine(1) was oxidated with activated MnO~2 to afford 2, 6-pyridinedicarboxaldehyde(2). The rection of o-nitrophenol and N-substituted di(chloroethyl) amine in DMF/K~2CO~3 obtained N-substituted 1,5-di(o-nitrophenoxy)-3-azapentane (3a-c), which were reduced with hydrazine hydrate/Raney Ni to afford N-substituted 1,5-di(o-aminophenoxy)-3-azapentane (4a-c). Schiff's base macrocyclic complexes (I-III) were synthesized using Ba^2^+ as template ion by reaction of (2) with compounds (4a-c) respectively. Complexes I and III were reduced with NaBH~4 to azamacrocyclic free ligands (IV, V).

Key words: SCHIFF BASE, NITROPHENOL P, MACROCYCLIC COMPOUNDS, PYRIDINE P, PENTANE P, NITROGEN HETEROCYCLICS, ETHANAMINE P, PYRIDINE P, COMPLEX COMPOUNDS, SYNTHESIS