The synthesis and biological activity of alkyl 4-(nitrophenyl)-3-thio-allophanate

Chin. J. Org. Chem. ›› 1998, Vol. 18 ›› Issue (4): 342-346. Previous Articles Next Articles

Original Articles

4-(硝基苯基)-3-硫代脲酸烷基酯类的合成及其生物活性研究

黄志纾;刘煜;吴晓琳;蒋腊生;王植材;古练权;许东晖

中山大学化学与化学工程学院;中山大学生命科学院

发布日期:1998-08-25

The synthesis and biological activity of alkyl 4-(nitrophenyl)-3-thio-allophanate

HUANG ZHISHU;LIU YU;WU XIAOLIN;JIANG LASHENG;WANG ZHICAI;GU LIANQUAN;XU DONGHUI

Published:1998-08-25

Abstract

Nine thiourea derivatives of alkyl 4-(nitrophenyl)-3-thio-allophanate (1-9) have been synthesized by the reaction of various nitroaniline with alkoxycarbonyl isothiocyanates (Me or Et) and transesterification of methyl or ethyl 4-(nitrophenyl)-3-thio-allophanate (1-6) with excess Ti·(OBu-n)~4. The biological activity of 1-9, inhibiting the growth of agrobacterium, was investigated.

Key words: SULFOCARBAMIDES, TRANSESTERIFICATION, NITROBENZENE P, BENZAMINE P, TITANIC ACID P, BUTYL, NITROBENZENE P, BIOLOGICAL ACTIVITY, BUTYL, SYNTHESIS

CLC Number:

O627

Cite this article

HUANG ZHISHU;LIU YU;WU XIAOLIN;JIANG LASHENG;WANG ZHICAI;GU LIANQUAN;XU DONGHUI. The synthesis and biological activity of alkyl 4-(nitrophenyl)-3-thio-allophanate[J]. Chin. J. Org. Chem., 1998, 18(4): 342-346.

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4-(硝基苯基)-3-硫代脲酸烷基酯类的合成及其生物活性研究

The synthesis and biological activity of alkyl 4-(nitrophenyl)-3-thio-allophanate

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