Synthesis, Structure and Biological Activities of N-Arylaminocarbonyl-2-oxo/thio-thiazolidine

Chin. J. Org. Chem. ›› 2006, Vol. 26 ›› Issue (08): 1106-1110. Previous Articles Next Articles

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N-取代苯基-2-取代-1,3-噻唑烷-3-甲酰胺的合成、结构及生物活性

翁建全*^,1，沈德隆¹，谭成侠¹，欧晓明²

(¹浙江工业大学化学工程与材料学院杭州 310032)
(²国家南方农药创制中心湖南基地生测部长沙 410007)

收稿日期:2005-11-17 修回日期:2006-02-17 发布日期:2006-07-26
通讯作者: 翁建全

Synthesis, Structure and Biological Activities of N-Arylaminocarbonyl-2-oxo/thio-thiazolidine

WENG Jian-Quan*^,1,SHEN De-Long¹,TAN Cheng-Xia¹,OU Xiao-Ming²

(¹College of Chemical Engineering and Materials Science, Zhejiang University of Technology, Hangzhou 310032)
(²Bioassay Department, Hunan Branch of National Southern Pesti-cide Research Centre, Changsha 410007)

Received:2005-11-17 Revised:2006-02-17 Published:2006-07-26
Contact: WENG Jian-Quan

Abstract

In order to find new thiazole-heterocycle lead compounds, seventeen N-arylaminocarbonyl-2- oxo/thio-thiazolidine derivatives were synthesized from a coupling reaction of 2-oxo/thio-thiazolidine and aryl isocyanates catalyzed by Et₃N. Their structures were confirmed by ¹H NMR, IR, MS spectra and elemental analysis. The crystal structure of N-anilinocarbonyl-2-oxothiazolidine was determined by X-ray diffraction analysis. The preliminary bioassay showed that some of them exhibited certain fungicidal and insecticidal activities.

Key words: substituted phenyl isocyanate, biological activity, synthesis, structure, 2-oxo/thio-thiazolidine

Cite this article

WENG Jian-Quan*^,1,SHEN De-Long,TAN Cheng-Xia,OU Xiao-Ming². Synthesis, Structure and Biological Activities of N-Arylaminocarbonyl-2-oxo/thio-thiazolidine[J]. Chin. J. Org. Chem., 2006, 26(08): 1106-1110.

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N-取代苯基-2-取代-1,3-噻唑烷-3-甲酰胺的合成、结构及生物活性

Synthesis, Structure and Biological Activities of N-Arylaminocarbonyl-2-oxo/thio-thiazolidine

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