Under microwave irradiation and using p-toluenesulfonic acid as a catalyst, the condensation reaction of 5-aryl-1,3-cyclohexanediones with o-anthranilonitrile afforded the corresponding N-substituted-2- aminobenzonitriles, which were followed by the intramolecular cyclization in the presence of potassium carbonate and cuprous chloride to give 3-aryl-9-amino-1,2,3,4-tetrahydroacridin-1-one. Then reduction of these acridinone compounds with lithium aluminum hydride in the ethyl ether afforded 3-aryl-9- amino-1,2,3,4-tetrahydroacridin-1-ol derivatives. The structures of all these new compounds were characterized by elemental analysis, IR and ¹H NMR and ¹³C NMR spectra.

Key words: derivative of acridinone, microwave irradiation, 5-aryl-1,3-cyclohexanedione, synthesis