Synthesis of α-Bromoarylketones Catalyzed by Ionic Liquid under Microwave Irradiation

Chin. J. Org. Chem. ›› 2011, Vol. 31 ›› Issue (03): 397-400. Previous Articles Next Articles

Notes

微波辐射下离子液体催化合成α-溴代芳基酮

李德富，刘卉闵，刘伟华，袁明月，张冬暖，张英群*

(河北农业大学理学院保定 071001)

收稿日期:2010-08-12 修回日期:2010-10-29 发布日期:2010-11-12
通讯作者: 张英群 E-mail:yingqun0203@163.com

Synthesis of α-Bromoarylketones Catalyzed by Ionic Liquid under Microwave Irradiation

LI De-Fu, LIU Hui-Min, LIU Wei-Hua, YUAN Ming-Yue, ZHANG Dong-Nuan, ZHANG Ying-Qun

(College of Sciences, Agricultural University of Hebei, Baoding 071001)

Received:2010-08-12 Revised:2010-10-29 Published:2010-11-12

Abstract

Seven α-bromoarylketones in yields of 73%～95% were obtained with ionic liquid as catalyst under microwave irradiation condition by the reaction of substituted acetophenones and N-bromosuccinim-ide. The optimal reaction conditions in methanol were as follows: n(aryl ketone)∶n(NBS)＝1∶1, acidic ionic liquid MIM-PS-CH₃SO₃H was 40 mol%, microwave power was 50 or 250 W. The reaction easily could be worked up with short reaction time, high yields and environmental friendliness. The catalyst could be reusable. The products were identified by ¹H NMR and IR spectra.

Key words: acetophenone, N-bromosuccinimide, α-bromoarylketone, microwave irradiation, ionic liq-uid

Cite this article

LI De-Fu, LIU Hui-Min, LIU Wei-Hua, YUAN Ming-Yue, ZHANG Dong-Nuan, ZHANG Ying-Qun. Synthesis of α-Bromoarylketones Catalyzed by Ionic Liquid under Microwave Irradiation[J]. Chin. J. Org. Chem., 2011, 31(03): 397-400.

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微波辐射下离子液体催化合成α-溴代芳基酮

Synthesis of α-Bromoarylketones Catalyzed by Ionic Liquid under Microwave Irradiation

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