Synthesis and Herbicidal Activity of Alkanoic Diacid Dial-kyl-didehydroabietyl-bis-oxadiazoles

Chin. J. Org. Chem. ›› 2011, Vol. 31 ›› Issue (07): 1069-1075. Previous Articles Next Articles

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脂肪族二酸二烷基双去氢枞基双噁二唑的合成及除草活性

马献力^1,2，陈丽¹，段文贵*^,1，岑波¹，董淑求¹

(¹广西大学化学化工学院南宁 530004)
(²桂林医学院药学院桂林 541004)

收稿日期:2010-12-01 修回日期:2011-02-16 发布日期:2011-03-04
通讯作者: 段文贵 E-mail:dwg118@gxu.edu.cn

Synthesis and Herbicidal Activity of Alkanoic Diacid Dial-kyl-didehydroabietyl-bis-oxadiazoles

Ma Xianli^1,2 Chen Li¹ Duan Wengui*^,1Cen Bo¹ Dong Shuqiu¹

(¹ College of Chemistry and Chemical Engineering, Guangxi University, Nanning 530004)
(² College of Pharmacy, Guilin Medical University, Guilin 541004)

Received:2010-12-01 Revised:2011-02-16 Published:2011-03-04
Contact: Wen-Gui DUAN E-mail:dwg118@gxu.edu.cn

Dehydroabietic acid chloride was prepared from dehydroabietic acid. Alkanoic diacid dihydrazides were synthesized using alkanoic diacids as starting materials via alkanoic diacid diethyl esters, followed by the reaction of alkanoic diacid dihydrazides with dehydroabietic acid chloride under phase transfer catalysis to afford N,N-didehydroabietacyl substituted alkanoic diacid dihydrazides. Five novel alkanoic diacid dialkyl-didehydroabietyl-bis-oxadiazoles were synthesized by the cyclization of N,N-didehy- droabietacyl substituted alkanoic diacid dihydrazides. The novel compounds were characterized by means of elemental analysis, ¹H NMR, ¹³C NMR, IR and MS techniques. The preliminary herbicidal activity test showed that compounds 6b～6e displayed good growth inhibition against root of rape at the concentration of 100 μg/mL, which had the inhi-bition rates ＞80%.

Key words: dehydroabietic acid, 1,3,4-oxadiazole, synthesis, herbicidal activity

CLC Number:

O626

Cite this article

MA Xian-Li, CHEN Li, DUAN Wen-Gui, CEN Bo, DONG Shu-Qiu. Synthesis and Herbicidal Activity of Alkanoic Diacid Dial-kyl-didehydroabietyl-bis-oxadiazoles[J]. Chin. J. Org. Chem., 2011, 31(07): 1069-1075.

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脂肪族二酸二烷基双去氢枞基双噁二唑的合成及除草活性

Synthesis and Herbicidal Activity of Alkanoic Diacid Dial-kyl-didehydroabietyl-bis-oxadiazoles

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