A Novel Synthetic Method of 1-Hydrazinophthalazine Hydrochloride

Chin. J. Org. Chem. ›› 2011, Vol. 31 ›› Issue (11): 1914-1916. Previous Articles Next Articles

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1-肼基-2,3-二氮杂萘盐酸盐的合成新方法

赵宝海，林吉茂^*

(山东大学化学与化工学院济南 250100)

收稿日期:2011-04-21 修回日期:2011-05-31 发布日期:2011-06-29
通讯作者: 赵宝海 E-mail:zhaobaohai0136@163.com

A Novel Synthetic Method of 1-Hydrazinophthalazine Hydrochloride

ZHAO Bao-Hai, LIN Ji-Mao

(School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100)

Received:2011-04-21 Revised:2011-05-31 Published:2011-06-29

In this paper, a novel synthetic method of 1-hydrazinophthalazine hydrochloride was reported starting from cheap and easily accessible phthalic anhydride. The 1-hydrazinophthalazine hydrochloride could be obtained by reduction, bromination, cyclization, substitution and acidification separately. The results showed that the advantages of this method were simply available starting materials, relatively high yield, easily purification of the product and low cost.

Key words: phthalic anhydride, 1-hydrazinophthalazine hydrochloride, synthesis

Cite this article

ZHAO Bao-Hai, LIN Ji-Mao. A Novel Synthetic Method of 1-Hydrazinophthalazine Hydrochloride[J]. Chin. J. Org. Chem., 2011, 31(11): 1914-1916.

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1-肼基-2,3-二氮杂萘盐酸盐的合成新方法

A Novel Synthetic Method of 1-Hydrazinophthalazine Hydrochloride

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