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Chin. J. Org. Chem. ›› 2005, Vol. 25 ›› Issue (05): 485-495.     Next Articles

含氟β-氨基酸及其衍生物的合成进展

彭荣达1，郝健*,1,2   

  1. (1上海大学化学系 上海 200436)
    (2中国科学院上海有机化学研究所 有机氟化学重点实验室 上海 200032)
  • 收稿日期:2004-07-12 修回日期:2004-10-29 发布日期:2004-04-30
  • 通讯作者: 郝健

Recent Development in the Synthesis of Fluorinated-AminoAcids and Their Derivatives

PENG Rong-Da1,HAO Jian*,1,2   

  1. (1 Department of Chemistry, Shanghai University, Shanghai 200436)
    (2 Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032)
  • Received:2004-07-12 Revised:2004-10-29 Published:2004-04-30
  • Contact: HAO Jian

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Fluorinated β-amino acids and their derivatives with specific bioactivities have been attracting great attention. This review briefly summarized the recent development in the methodologies for the synthesis of biologically important fluorinated β-amino acids and their derivatives with classification by the ways of the direct and indirect fluorination respectively.

Key words: fluorinated β-amino acid, building block, synthesis, development, bioactivity