Benzylation of rutin followed by hydrolysis afforded 3′,4′,7-O-tribenzylquercetin (3). Compound 3 was condensed with acetylglycosyl bromides in a two-phase system of chloroform-0.25 mol•L^－1 aqueous potassium carbonate using tetrabutyl ammonium bromide as catalyst to yield the protected glycosides 4a～4d. Removal of protecting group led to target products 1a～1d and the structures of such products 1a～1d were confirmed by IR, ¹H NMR, MS spectra and elemental analysis.

Key words: phase transfer catalysis, quercetin-3-O-glycoside, synthesis, 3′,4′_,7-O-tribenzylquercetin